ReviewMicroorganisms2026
Reclaiming the Microbial Battlefield: Adjuvant Strategies to Overcome Antibiotic Resistance.
Review in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The escalation of antibiotic resistance constitutes a significant global health crisis, urgently demanding innovative strategies to restore and amplify the effectiveness of our existing antimicrobial arsenal. This review systematically explores the diverse landscape of antibiotic adjuvants, beginning with an elucidation of their classifications and profound mechanisms of action. We meticulously detail various categories of these agents, encompassing both synthetic compounds and naturally derived molecules, highlighting their crucial functions in potentiating antibiotic activity through mechanisms such as enhancing bacterial cell permeability, modulating the expression of resistance-conferring genes and optimizing drug-target interactions. Furthermore, we critically assess current screening methodologies, particularly the advancements in high-throughput approaches, and their implications for the identification and validation of novel adjuvant candidates. The review underscores the potential of antibiotic adjuvants as a promising frontier in our global endeavor to overcome bacterial resistance and ensure the sustained utility of antimicrobial medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.