ArticleMicromachines2026
A Dissolving Microneedle Design for Poorly Water-Soluble Drugs for Enhanced Skin Permeation and Transdermal Delivery Fabricated Using 3D Printing.
Article in Micromachines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
1 author.
Funding
Abstract
Microneedles (MNs) offer a transformative platform for transdermal drug delivery, though balancing structural precision with mechanical robustness remains challenging. This study utilized SLA 3D printing to fabricate high-resolution MN masters, systematically evaluating printing angles (0° to 60°) and aspect ratios to optimize fidelity. A 45° printing angle was found to significantly enhance tip sharpness and insertion efficiency. These optimized structures served as templates for flurbiprofen (FLU)-loaded dissolving MNs (DMNs) fabricated via a bilayered casting method. We investigated the impact of geometric architectures-conical, pyramidal, and star-type-on functional performance. Mechanical testing using Parafilm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.