Evidence map›Paper›PMID 41900127›Full record

ArticleMolecules (Basel, Switzerland)2026

Nanostructured Lipid Carriers as Physicochemical Modulators of Complex Natural Extracts: Release Behavior and Bile-Induced Remodeling in Biorelevant Media.

Javiera Carrasco-Rojas, Javiera Solas-Soto, Rubén Veas-Albornoz, Carlos F Lagos, Mario J Simirgiotis, Francisco Arriagada, Andrea C Ortiz

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Javiera Carrasco-RojasDepartamento de Ciencias y Tecnología Farmacéutica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago 8380494, Chile.ORCID 0000-0002-0711-433X
Javiera Solas-SotoEscuela de Química y Farmacia, Facultad de Ciencias, Universidad San Sebastián, Lota 2465, Santiago 7510157, Chile.ORCID 0009-0009-6237-1775
Rubén Veas-AlbornozEscuela de Química y Farmacia, Facultad de Ciencias, Universidad San Sebastián, Lota 2465, Santiago 7510157, Chile.ORCID 0009-0004-8038-2770
Carlos F LagosEscuela de Química y Farmacia, Facultad de Ciencias, Universidad San Sebastián, Lota 2465, Santiago 7510157, Chile.ORCID 0000-0002-5432-9747
Mario J SimirgiotisInstituto de Farmacia, Facultad de Ciencias, Universidad Austral de Chile, Campus Isla Teja, Valdivia 5090000, Chile.ORCID 0000-0003-4552-3123
Francisco ArriagadaDepartamento de Ciencias y Tecnología Farmacéutica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago 8380494, Chile.ORCID 0000-0001-8404-6492
Andrea C OrtizEscuela de Química y Farmacia, Facultad de Ciencias, Universidad San Sebastián, Lota 2465, Santiago 7510157, Chile.ORCID 0000-0001-9232-4632

Funding

Agencia Nacional de Investigación y Desarrollo 11240466Agencia Nacional de Investigación y Desarrollo 1220075Agencia Nacional de Investigación y Desarrollo FB210008
6 · The paper itself

Abstract

Propolis is a chemically complex natural product with recognized antioxidant potential, but its compositional heterogeneity and poor aqueous solubility complicate formulation and interpretation of in vitro release behavior. In this study, a nanostructured lipid carrier (NLC) based on Gelucire

Indexed as

BileBiological ProductsDrug CarriersLipidsNanostructuresPropolisAntioxidantsDrug LiberationHep G2 CellsHumansSolubilityAntioxidantsBiological ProductsDrug CarriersLipidsPropolisbiorelevant gastrointestinal mediaHepG2nanostructured lipid carrierspropolis

Identifiers

PMID41900127
PMCPMC13029395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.