Evidence map›Paper›PMID 41900095›Full record

SynthesisMolecules (Basel, Switzerland)2026

Agri-Food Biowaste Bioactives for Biopesticides: A Circular Economy Solution with Industry 4.0?

Thiago F Soares, Rita C Alves, Maria Beatriz P P Oliveira

Abstract readSystematic Review
In one paragraph

Synthesis in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Thiago F SoaresLAQV-REQUIMTE, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo 228, 4050-313 Porto, Portugal.ORCID 0000-0002-1489-1268
Rita C AlvesLAQV-REQUIMTE, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo 228, 4050-313 Porto, Portugal.ORCID 0000-0002-5053-513X
Maria Beatriz P P OliveiraLAQV-REQUIMTE, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo 228, 4050-313 Porto, Portugal.ORCID 0000-0002-6767-6596

Funding

Fundação para a Ciência e Tecnologia 2022.13829.BD (PhD grant)Fundação para a Ciência e Tecnologia UID/50006 - Laboratório Associado para a Química Verde - Tecnologias e Processos Limpos
6 · The paper itself

Abstract

The widespread use of synthetic pesticides has ensured crop productivity but has also raised serious environmental and human health concerns, including water contamination, biodiversity loss, and intoxication risks. In this context, global strategies for sustainable agriculture, safer alternatives are urgently needed. This systematic review, conducted in accordance with PRISMA guidelines, examines the potential of agri-food by-products as sources of bioactive compounds for biopesticide development within a circular economy framework. Residues from major agri-food chains, including the olive, potato, banana, citrus, and winery industries, were systematically analyzed with respect to their phytochemical composition, such as phenolics, flavonoids, terpenoids, fatty acids, and essential oils, and their reported bioactivity against insects, weeds, fungi, bacteria, and nematodes. The mechanisms of action, technological recovery strategies, and formulation challenges are critically discussed. Additionally, regulatory challenges and opportunities in the European and U.S. markets are described together with the role of Industry 4.0 technologies in optimizing recovery processes and product development. By promoting biopesticides from agri-food biowaste, this approach contributes to sustainable production (SDG 12), innovation in industrial processes (SDG 9), and the protection of terrestrial and aquatic ecosystems (SDGs 14 and 15), positioning food industry residues as a strategic resource for green crop protection.

Indexed as

AgricultureBiological Control AgentsPhytochemicalsAnimalsFood IndustryFood Loss and WasteHumansBiological Control AgentsFood Loss and WastePhytochemicalsby-products valorizationgreen chemistryphytochemicalsplant protectionsustainable agriculture

Identifiers

PMID41900095
PMCPMC13028968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.