Electrochemical Sensing of Doxorubicin in Breast Cancer Cells Based on Membrane-Permeation Strategy.

Lizhen Yu, Dandan Wang, Zhongtao Hu, Xuefeng Hou, Shuxue Wang, Wenzhi Zhang, Lihua Li

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lizhen YuDrug Research and Development Center, School of Pharmacy, Wannan Medical College, Wuhu 241000, China.

Dandan WangDrug Research and Development Center, School of Pharmacy, Wannan Medical College, Wuhu 241000, China.

Zhongtao HuDrug Research and Development Center, School of Pharmacy, Wannan Medical College, Wuhu 241000, China.

Xuefeng HouDrug Research and Development Center, School of Pharmacy, Wannan Medical College, Wuhu 241000, China.

Shuxue WangDrug Research and Development Center, School of Pharmacy, Wannan Medical College, Wuhu 241000, China.

Wenzhi ZhangDrug Research and Development Center, School of Pharmacy, Wannan Medical College, Wuhu 241000, China.

Lihua LiDrug Research and Development Center, School of Pharmacy, Wannan Medical College, Wuhu 241000, China.

Funding

Anhui Province New Era Education Quality Project 2024yjsxxsfkc044College Students' Innovative Entrepreneurial Training Plan Program S202510368003Quality Assurance and Teaching Reform Project of Wannan Medical College 2024jc02Quality Assurance and Teaching Reform Project of Wannan Medical College 2024xxkc06the Project of Anhui Laboratory of Molecule-Based Materials of the College of Chemistry and Materials Science of Anhui Normal University fzj22016

6 · The paper itself

Abstract

Monitoring the concentration of doxorubicin (DOX) was critical for tumor treatment, but existing methods failed to cross cell membrane. Here, an electrochemical platform for intracellular DOX detection in MCF-7 cells based on membrane-permeation strategy was developed. A modified gold electrode was prepared via electrodepositing AuNPs and assembling SH-DNA. Concurrently, the silica nanosphere/gold nanocluster-circular transmembrane peptide (SiO

Indexed as

Biosensing TechniquesBreast NeoplasmsCell Membrane PermeabilityDoxorubicinElectrochemical TechniquesElectrodesFemaleGoldHumansMCF-7 CellsMetal NanoparticlesDoxorubicinGolddoxorubicinelectrochemical sensingiRGDMCF-7 cellsmembrane permeation

Identifiers

PMID41900030

DOI10.3390/molecules31060931

PMCPMC13029333

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.