ArticleBioengineering (Basel, Switzerland)2026
A Mechanistic, Architecture-Dependent Study Combining Experiments and Molecular Dynamics to Explain AMP Release from GO-PEI Coatings.
Adriana de América, María José Fritte, Paola Alarcón, Karel Mena-Ulecia, Gonzalo Recio-Sánchez, Klaus Rischka, Marcos Rocha Diniz Silva, Matheus Santos Dias, Camila Marchetti Maroneze, Cecilia de Carvalho Castro Silva and 1 more
Abstract read
In one paragraphArticle in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
11 authors.
Adriana de AméricaDepartamento de Ciencias Físicas y Matemáticas, Universidad Católica de Temuco, Temuco 4813302, Chile.
María José FritteDepartamento de Ciencias Físicas y Matemáticas, Universidad Católica de Temuco, Temuco 4813302, Chile.
Paola AlarcónDepartamento de Ciencias Físicas y Matemáticas, Universidad Católica de Temuco, Temuco 4813302, Chile.
Karel Mena-UleciaNúcleo de Investigación en Bioproductos y Materiales Avanzados (BioMA), Universidad Católica de Temuco, Temuco 4813302, Chile.ORCID 0000-0001-6651-511X Gonzalo Recio-SánchezFacultad de Ingeniería, Arquitectura y Diseño, Universidad San Sebastián, Concepción 4080871, Chile.
Klaus RischkaDepartment of Adhesive Bonding Technology and Surfaces, Fraunhofer Institute for Manufacturing Technology and Advanced Materials (IFAM), 28359 Bremen, Germany.ORCID 0000-0003-3427-4037 Marcos Rocha Diniz SilvaMackenzie School of Engineering, Mackenzie Presbyterian University, São Paulo 01302-907, Brazil.ORCID 0000-0002-9108-3192 Matheus Santos DiasMackenzie School of Engineering, Mackenzie Presbyterian University, São Paulo 01302-907, Brazil.
Camila Marchetti MaronezeMackenzie School of Engineering, Mackenzie Presbyterian University, São Paulo 01302-907, Brazil.ORCID 0000-0002-6835-4476 Cecilia de Carvalho Castro SilvaMackenzie School of Engineering, Mackenzie Presbyterian University, São Paulo 01302-907, Brazil.ORCID 0000-0003-3933-1838 Jacobo Hernandez-MontelongoDepartamento de Ciencias Físicas y Matemáticas, Universidad Católica de Temuco, Temuco 4813302, Chile.ORCID 0000-0002-1510-3470 Funding
Coordenação de Aperfeicoamento de Pessoal de Nível Superior 408248/2023-8Financiadora de Estudos e Projetos 1151/22Financiadora de Estudos e Projetos 1755/22Fondo Nacional de Desarrollo Científico y Tecnológico 1230553INCT NanoVida 406079/2022-6National Council for Scientific and Technological Development 313091/2022-6National Laboratory for High Performance Computing CCSS210001
6 · The paper itselfAbstract
This study investigates two graphene oxide (GO)-based coating architectures on urinary catheter substrates-layered (PEI+GO) and embedded (PEI/GO)-loaded with antimicrobial peptides (E14LKK and fLFB), with the aim of elucidating how coating structure governs peptide retention and release. Physicochemical and morphological characterization confirmed distinct coating architectures and thicknesses. Molecular dynamics simulations were employed to probe GO-peptide and PEI-peptide interactions, revealing weaker binding of fLFB to GO relative to PEI, consistent with enhanced peptide mobility. Antibacterial performance against
Indexed as
antimicrobial peptidescoatingsgraphene oxidemolecular dynamicsurinary catheters
Identifiers
PMID41899872
PMCPMC13023436
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