Evidence map›Paper›PMID 41899840›Full record

ReviewBioengineering (Basel, Switzerland)2026

Advancing Microplastic and Nanoplastic Toxicity Assessment: Insights from Human Organoid Models.

Lingling Ge, Yingying Lan, Jing Gong, Xue Gao, Francesco Faiola, Shaocheng Zhang, Minghui Li

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lingling GeDepartment of Laboratory Medicine, The Second Affiliated Hospital of Chengdu Medical College (Nuclear Industry 416 Hospital), Chengdu 610051, China.
Yingying LanSouthwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Jing GongDepartment of Infectious Diseases, Institute for Viral Hepatitis, The Second Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China.
Xue GaoKey Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400045, China.
Francesco FaiolaState Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.ORCID 0000-0002-3512-8253
Shaocheng ZhangDepartment of Laboratory Medicine, The Second Affiliated Hospital of Chengdu Medical College (Nuclear Industry 416 Hospital), Chengdu 610051, China.ORCID 0000-0003-3620-1616
Minghui LiSouthwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.

Funding

National Natural Science Foundation of China 82204083
6 · The paper itself

Abstract

Evidence has demonstrated that microplastics (MPs) and nanoplastics (NPs) exerted toxic effects on animal models; our understanding of their potential toxicity to human health remains limited due to the lack of human-relevant in vitro models. Human stem cell-derived organoids are sophisticated and multicellular structures that could effectively mimic the key features of native organs and tissues. To date, human organoids have been widely used in toxicology. This study reviews the current application of human organoids in the toxicity assessment of MPs and NPs. Current limitations and future perspectives are discussed. Cutting-edge technologies combined with organoids are expected to provide new insights for illustrating the potential toxicity of MPs and NPs.

Indexed as

human organoidsmicroplasticsnanoplasticsorganoid toxicologytoxicity assessment

Identifiers

PMID41899840
PMCPMC13023869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.