Evidence map›Paper›PMID 41899774›Full record

SynthesisInternational journal of environmental research and public health2026

Association Between

Athina Smallwood, Elizabeth Akam, David John Hunter, Monica Singh, Puneetpal Singh, Sarabjit Mastana

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in International journal of environmental research and public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Athina SmallwoodSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough LE11 3TU, UK.ORCID 0009-0004-7361-3542
Elizabeth AkamSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough LE11 3TU, UK.ORCID 0000-0002-8784-3742
David John HunterSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough LE11 3TU, UK.ORCID 0000-0003-1060-3334
Monica SinghDepartment of Human Genetics, Punjabi University, Patiala 147002, India.
Puneetpal SinghDepartment of Human Genetics, Punjabi University, Patiala 147002, India.ORCID 0000-0003-2154-4261
Sarabjit MastanaSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough LE11 3TU, UK.ORCID 0000-0002-9553-4886

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEssential hypertension (EH) refers to elevated arterial blood pressure with unknown etiology, which becomes more prevalent with age. Although the D allele of the

methodsCase-control and cohort studies published in the last 20 years were reviewed from the main databases (PubMed, Scopus and Embase) using specific inclusion and exclusion criteria. Genotype data were used in meta-analyses using different genetic models.

resultsTwenty-two studies with 7690 participants (3886 cases and 3804 controls) were included. Significant associations were observed between the

conclusionsThe findings support a significant association between the

Indexed as

Essential HypertensionHypertensionPeptidyl-Dipeptidase APolymorphism, GeneticGenetic Predisposition to DiseaseHumansACE protein, humanPeptidyl-Dipeptidase AACE (I/D)AfricanChineseessential hypertensionEuropeanHispanicIndianMiddle Eastern

Identifiers

PMID41899774
PMCPMC13027306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.