Evidence map›Paper›PMID 41899601›Full record

ArticleCancers2026

Early Ibrutinib Dose Modifications in CLL: A Post Hoc Analysis of the Real-World EVIdeNCE Study.

Stefano Molica, Potito Rosario Scalzulli, Lydia Scarfò, Carla Minoia, Roberta Murru, Paolo Sportoletti, Francesco Albano, Nicola Di Renzo, Alessandro Sanna, Luca Laurenti and 28 more

Abstract read
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Stefano MolicaHull York Medical School, University of Hull, Hull HU6 7RX, UK.ORCID 0000-0003-2795-6507
Potito Rosario ScalzulliOspedale "Casa Sollievo Della Sofferenza", 71013 San Giovanni Rotondo, Italy.
Lydia ScarfòSchool of Medicine, Università Vita Salute San Raffaele, 20132 Milan, Italy.
Carla MinoiaHematology Unit, IRCCS Istituto Tumori "Giovanni Paolo II", 70124 Bari, Italy.ORCID 0000-0002-5707-0689
Roberta MurruHematology and Stem Cell Transplantation Unit, Ospedale Oncologico A. Businco, ARNAS G. Brotzu, 09121 Cagliari, Italy.ORCID 0000-0001-9792-9542
Paolo SportolettiHematology and Clinical Immunology Section, Department of Medicine and Surgery, Center for Hemato-Oncological Research (CREO), University of Perugia, 06123 Perugia, Italy.ORCID 0000-0002-5630-9862
Francesco AlbanoHematology and Stem Cell Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", 70121 Bari, Italy.ORCID 0000-0001-7926-6052
Nicola Di RenzoUOC Ematologia e Trapianto di Cellule Staminali, PO "Vito Fazzi", ASL Lecce, 73100 Lecce, Italy.
Alessandro SannaHematology Unit, AOU Careggi, 50134 Florence, Italy.ORCID 0000-0002-5015-381X
Luca LaurentiPoliclinico A. Gemelli, 00168 Rome, Italy.ORCID 0000-0002-8327-1396
Massimo MassaiaSC Ematologia, AO S. Croce e Carle, 12100 Cuneo, Italy.
Ramona CassinFondazione IRCCS Cà Granda Ospedale Maggiore Policlinico of Milan, 20122 Milano, Italy.
Marta CosciaDepartment of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.
Caterina PattiUOC Oncoematologia, Ospedali Riuniti Villa Sofia-Cervello, 90146 Palermo, Italy.
Elsa PenneseUOC Ematologia, Dipartimento Oncologico-Ematologico, PO Santo Spirito, 65124 Pescara, Italy.
Agostino TafuriEmatologia, AOU Sant'Andrea, Sapienza Università di Roma, 00185 Rome, Italy.
Annalisa ChiarenzaUOC Ematologia, AOU Policlinico G.Rodolico-San Marco, 95123 Catania, Italy.
Piero GalieniUOC Ematologia e Terapia Cellulare, Ospedale Mazzoni, 63100 Ascoli Piceno, Italy.ORCID 0000-0002-0793-264X
Omar PerbelliniUOC Ematologia, Azienda ULSS 8 Berica, 36100 Vicenza, Italy.ORCID 0000-0002-8278-8916
Carmine SelleriHematology and Bone Marrow Transplant Center, Department of Medicine and Surgery, University of Salerno, 84084 Salerno, Italy.ORCID 0000-0002-5861-8984
Catello CalifanoUOC Ematologia, PO Andrea Tortora-Pagani, 84016 Pagani, Italy.
Felicetto FerraraAORN Antonio Cardarelli, 80131 Naples, Italy.ORCID 0000-0003-3721-5403
Antonio CuneoHematology Unit, Università Degli Studi di Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-2001-1308
Marco MurinedduEmatologia, Ospedale San Francesco ASL Nuoro, 08100 Nuoro, Italy.
Gaetano PalumboSC Ematologia, AOU Policlinico Foggia, 71122 Foggia, Italy.
Ilaria ScortechiniAzienda Ospedaliero Universitaria delle Marche, 60126 Ancona, Italy.
Alessandra TedeschiDivisione di Ematologia, ASST GOM Niguarda, 20162 Milan, Italy.
Livio TrentinUOC Ematologia, Dipartimento di Medicina, Università di Padova, 35122 Padua, Italy.ORCID 0000-0003-1222-6149
Marzia VarettoniDivisione di Ematologia, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.ORCID 0000-0001-7304-1629
Fabrizio PaneUniversità di Napoli Federico II, 80138 Naples, Italy.ORCID 0000-0003-2563-4125
Francesco MerliEmatologia, AUSL-IRCCS Reggio Emilia, 42122 Reggio Emilia, Italy.
Lucia MorelloHumanitas Cancer Center, IRCCS Humanitas Research Hospital, 20089 Rozzano, Italy.
Gerardo MusuracaIRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.ORCID 0000-0003-1947-1032
Monica TaniHaematology Unit, Ospedale S. Maria delle Croci, 48121 Ravenna, Italy.
Adalberto IbaticiIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Maria PalmaJohnson & Johnson Innovative Medicine, 20126 Milan, Italy.
Danilo ArientiJohnson & Johnson Innovative Medicine, 20126 Milan, Italy.
Francesca Romana MauroHematology, Department of Translational and Precision Medicine, Sapienza Università di Roma, 00185 Rome, Italy.ORCID 0000-0003-2425-9474

Funding

Johnson & Johnson N/A
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

clinical outcomesCLLdose modificationsibrutinib adherencepatient comorbidities

Identifiers

PMID41899601
PMCPMC13024652

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.