Evidence map›Paper›PMID 41899598›Full record

ArticleCancers2026

Characterization of HER2-Positive Murine Breast Cancer Models for Investigating HER2-Targeted Therapy and Immunotherapy.

Yun Lu, Benjamin P Lee, Abbigael V Eli, Shannon E Lynch, Ar Rafi Md Faisal, Jonathan Moye, Anna G Sorace

Abstract read
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yun LuDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-4785-3401
Benjamin P LeeDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-6937-2211
Abbigael V EliGraduate Biomedical Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0001-9014-2659
Shannon E LynchDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-0325-2823
Ar Rafi Md FaisalGraduate Biomedical Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Jonathan MoyeDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Anna G SoraceDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-3640-3966

Funding

Medical Scientist Training ProgramT32GM156741 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Talene Alene Yacoubian · 2025 to 2026
$2.5M
Personalizing immunotherapy in HER2+ breast cancer through quantitative imagingR01CA240589 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SORACE, ANNA C · 2020 to 2023
$1.6M
Mathematical modeling and molecular imaging to maximize response while minimizing toxicities from systemic therapies in preclinical models of breast cancerR01CA276540 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SORACE, ANNA C, YANKEELOV, THOMAS E · 2023 to 2025
$1.4M
NCI NIH HHS R01CA240589NCI NIH HHS R01CA276540NIGMS NIH HHS T32GM156741
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anti-CTLA-4anti-PD-1brain metastasisbreast cancerHER2+ breast cancerT-DM1T-DXdtrastuzumabtucatinib

Identifiers

PMID41899598
PMCPMC13024896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.