ArticleCancers2026
A Pathomics-Based Prognostic Model for Disease-Free Survival in Resected Gastric Cancer.
Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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16 authors.
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Abstract
objectivesThis study aims to develop and validate a prognostic risk model by integrating pathomics features with clinical variables to predict disease-free survival (DFS) in patients with gastric cancer (GC).
methodsPatients with GC who were pathologically diagnosed and subsequently treated with curative gastrectomy and D2 lymphadenectomy at the Fifth Affiliated Hospital of Wenzhou Medical University between January 2017 and April 2023 were retrospectively enrolled and assigned to a training cohort (
resultsA total of 16 pathomics features were selected, and the cut-off for the pathomics scores was set at 0.27. High-risk patients exhibited significantly worse DFS compared to low-risk patients in both the training cohort (HR = 4.57, 95% CI: 3.118-6.697,
conclusionsA clinic-pathomics model integrating pathomics features with clinical data provides a reliable tool for DFS prediction in patients with GC, which facilitates individualized DFS predictions and personalized treatment strategies.
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