Evidence map›Paper›PMID 41899465›Full record

ArticleCurrent issues in molecular biology2026

Effects of Citicoline-Based Supplementation on Lipid Peroxidation Markers and Sirtuin-1 Expression in Ischemic Stroke.

Todorka Sokrateva, Bogdan Roussev, Daniela V Vankova, Deyana G Vankova, Diana Ivanova, Mihael Tsalta-Mladenov, Darina Georgieva, Miglena N Nikolova, Galya Mihaylova, Milka A Nashar

Abstract read
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In one paragraph

Article in Current issues in molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Todorka SokratevaDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University "Prof. Dr Paraskev Stoyanov"-Varna, 9002 Varna, Bulgaria.
Bogdan RoussevDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University "Prof. Dr Paraskev Stoyanov"-Varna, 9002 Varna, Bulgaria.
Daniela V VankovaDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University "Prof. Dr Paraskev Stoyanov"-Varna, 9002 Varna, Bulgaria.ORCID 0009-0003-0218-2792
Deyana G VankovaDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University "Prof. Dr Paraskev Stoyanov"-Varna, 9002 Varna, Bulgaria.ORCID 0000-0002-6542-538X
Diana IvanovaDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University "Prof. Dr Paraskev Stoyanov"-Varna, 9002 Varna, Bulgaria.ORCID 0000-0002-4502-081X
Mihael Tsalta-MladenovDepartment of Neurology and Neuroscience, Faculty of Medicine, Medical University "Prof. Dr Paraskev Stoyanov"-Varna, 9002 Varna, Bulgaria.ORCID 0000-0001-9898-3962
Darina GeorgievaSecond Clinic of Neurology with ICU and Stroke Center, University Hospital "St. Marina", 9010 Varna, Bulgaria.
Miglena N NikolovaDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University "Prof. Dr Paraskev Stoyanov"-Varna, 9002 Varna, Bulgaria.
Galya MihaylovaDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University "Prof. Dr Paraskev Stoyanov"-Varna, 9002 Varna, Bulgaria.
Milka A NasharDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University "Prof. Dr Paraskev Stoyanov"-Varna, 9002 Varna, Bulgaria.ORCID 0000-0003-0526-3996

Funding

European Union-NextGenerationEU, Medical University of Varna BG-RRP-2.004-0009-C02; and Science Fund Projects 21015 and 24007
6 · The paper itself

Abstract

Ischemic stroke (IS) is associated with pronounced oxidative stress and lipid peroxidation, which contribute to secondary neuronal damage. This study explored the effects of a six-month intervention with a new formulation containing citicoline, vitamin C, and extracts from green tea and aronia (Cytodeox™) on arachidonic acid (AA) metabolism, lipid peroxidation assessed by total 8-iso-prostaglandin F

Indexed as

8-iso-prostaglandin F2αarachidonic acidciticolineischemic strokelipid peroxidationneuroprotectionnutraceutical supplementationoxidative stressSirtuin-1

Identifiers

PMID41899465
PMCPMC13024967

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.