Evidence map›Paper›PMID 41899392›Full record

ArticleCurrent issues in molecular biology2026

Triptonide Suppresses AML via PI3K/AKT Signaling: A Network Pharmacology Approach Validated by Molecular Docking and Experimental Studies.

Lixia Song, Jing Meng, Huijie Li, Wanxin Fu, Kun Hong, Shengnan Shen, Zheping Zhang, Shilan Ding, Shengpeng Li, Zifan Zhang and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current issues in molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Lixia SongInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Jing MengInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Huijie LiInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Wanxin FuSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing 102401, China.
Kun HongInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Shengnan ShenInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Zheping ZhangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Shilan DingInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Shengpeng LiInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Zifan ZhangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Weijian BeiInstitute of Chinese Medicinal Sciences, Guangdong TCM Key Laboratory against Metabolic Diseases, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Hairu HuoInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Yuqing TanInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Feng SuiInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Li LiuInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.ORCID 0000-0002-9146-6898

Funding

Fundamental Research Funds for the Central public welfare research institutes ZXKT22041Fundamental Research Funds for the Central public welfare research institutes ZZ13-YQ-054National Natural Science Foundation of China 82173998National Natural Science Foundation of China 82174101National Natural Science Foundation of China 82374057National Natural Science Foundation of China 82374160
6 · The paper itself

Abstract

Triptonide (TN), a natural bioactive compound derived from

Indexed as

acute myeloid leukemiamolecular dockingmolecular dynamics simulationsnetwork pharmacologytriptonide

Identifiers

PMID41899392
PMCPMC13025876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.