Evidence map›Paper›PMID 41899108›Full record

ArticleJournal of clinical medicine2026

Health-Related Quality of Life in Radiologically Isolated Syndrome Resembles Relapsing-Remitting Multiple Sclerosis.

Julián Benito-León, María Díez-Cirarda, Mariano Ruiz-Ortiz, Yolanda Aladro, Constanza Cuevas, Ángela Domingo-Santos, Victoria Galán Sánchez-Seco, Andrés Labiano-Fontcuberta, Ana Gómez-López, Paula Salgado-Cámara and 8 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Julián Benito-LeónDepartment of Neurology, 12 de Octubre University Hospital, 28041 Madrid, Spain.ORCID 0000-0002-1769-4809
María Díez-CirardaDepartment of Neurology, Hospital Universitario Clínico San Carlos, Health Research Institute "San Carlos" (IdISCC), 28040 Madrid, Spain.ORCID 0000-0001-6768-189X
Mariano Ruiz-OrtizDepartment of Neurology, 12 de Octubre University Hospital, 28041 Madrid, Spain.ORCID 0000-0001-9993-1865
Yolanda AladroDepartment of Neurology, Getafe University Hospital, 28905 Getafe, Spain.
Constanza CuevasDepartment of Neurology, Hospital Universitario Clínico San Carlos, Health Research Institute "San Carlos" (IdISCC), 28040 Madrid, Spain.ORCID 0000-0001-9192-9971
Ángela Domingo-SantosDepartment of Neurology, 12 de Octubre University Hospital, 28041 Madrid, Spain.
Victoria Galán Sánchez-SecoDepartment of Neurology, 12 de Octubre University Hospital, 28041 Madrid, Spain.
Andrés Labiano-FontcubertaDepartment of Neurology, 12 de Octubre University Hospital, 28041 Madrid, Spain.
Ana Gómez-LópezDepartment of Neurology, 12 de Octubre University Hospital, 28041 Madrid, Spain.ORCID 0000-0002-5063-439X
Paula Salgado-CámaraDepartment of Neurology, 12 de Octubre University Hospital, 28041 Madrid, Spain.ORCID 0000-0001-9218-5206
Lucienne Costa-FrossardDepartment of Neurology, Ramón y Cajal University Hospital, Red Española de Esclerosis Múltiple (REEM), Red de Enfermedades Inflamatorias (REI), 28034 Madrid, Spain.ORCID 0000-0002-6512-4413
Enric MonrealDepartment of Neurology, Ramón y Cajal University Hospital, Red Española de Esclerosis Múltiple (REEM), Red de Enfermedades Inflamatorias (REI), 28034 Madrid, Spain.ORCID 0000-0003-3293-0125
Susana Sainz de la MazaDepartment of Neurology, Ramón y Cajal University Hospital, Red Española de Esclerosis Múltiple (REEM), Red de Enfermedades Inflamatorias (REI), 28034 Madrid, Spain.ORCID 0000-0001-8605-0049
Jorge Matías-GuiuDepartment of Medicine, Faculty of Medicine, Complutense University, 28040 Madrid, Spain.ORCID 0000-0001-8162-9043
Paloma Montero-EscribanoDepartment of Neurology, Hospital Universitario Clínico San Carlos, Health Research Institute "San Carlos" (IdISCC), 28040 Madrid, Spain.
María Luisa Martínez-GinésDepartment of Neurology, Gregorio Marañón General University Hospital, 28007 Madrid, Spain.
Lucía Ayuso-PeraltaDepartment of Neurology, Príncipe de Asturias University Hospital, 28805 Alcalá de Henares, Spain.
Jordi A Matías-GuiuDepartment of Medicine, Faculty of Medicine, Complutense University, 28040 Madrid, Spain.ORCID 0000-0001-5520-2708

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EuroQolFAMSfatiguemultiple sclerosisquality of liferadiologically isolated syndrome

Identifiers

PMID41899108
PMCPMC13027015

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.