Evidence map›Paper›PMID 41899034›Full record

ReviewJournal of clinical medicine2026

Pattern of Oculomotor Findings in Children with Attention Deficit/Hyperactivity Disorder in Relation to Methylphenidate Treatment.

Claudia Brogna, Valentina Napoli, Laura Castellini, Federica Mirra, Simona Sestito, Giuseppe Marsella, Maria Luisa Piscopiello, Valentina Cima, Daniela Ricci, Annabella Salerni and 3 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Claudia BrognaPediatric Neurology Unit, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Valentina NapoliPediatric Neurology Unit, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Laura CastelliniPediatric Neurology Unit, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Federica MirraPediatric Neurology Unit, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Simona SestitoPediatric Neurology Unit, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Giuseppe MarsellaPediatric Neurology Unit, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Maria Luisa PiscopielloPediatric Neurology Unit, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Valentina CimaOphthalmology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Daniela RicciNational Centre of Services and Research for the Prevention of Blindness and Rehabilitation of Visually Impaired, IAPB Italia Onlus, 00168 Rome, Italy.
Annabella SalerniOphthalmology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Gianluigi Di CesarePrevention and Early Intervention Complex Operative Unit, Department of Mental Health, ASL Roma 1, 00193 Rome, Italy.
Patrizia BrognaPrevention and Early Intervention Complex Operative Unit, Department of Mental Health, ASL Roma 1, 00193 Rome, Italy.ORCID 0000-0003-4857-6212
Domenico M RomeoPediatric Neurology Unit, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0002-6229-1208

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Attention-Deficit/Hyperactivity Disorder (ADHD) may be associated with alterations in eye movements, which in turn may reflect dysfunctions in executive functions and sensorimotor integration processes. This review analyzed the pattern of oculomotor findings of pediatric populations diagnosed with ADHD with or without methylphenidate (MPH) treatment, with the aim of systematically describing the oculomotor abnormalities observed in affected children. A total of 24 studies were analyzed. The results showed that children with ADHD exhibit increased latency, a higher number of directional errors in prosaccade and antisaccade tasks, as well as intrusions during fixation and a higher frequency of microsaccades and involuntary blinks. Furthermore, studies involving the administration of MPH showed an improvement in oculomotor control, with a reduction in errors and a modulation of latency and oculomotor inhibition. These findings confirmed the potential role of oculomotor parameters as objective and non-invasive biomarkers for exploring the neurofunctional correlates of ADHD and for evaluating the effects of pharmacological treatment.

Indexed as

ADHDmethylphenidateoculomotor alterations

Identifiers

PMID41899034
PMCPMC13026225

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.