Evidence map›Paper›PMID 41898848›Full record

ArticleGenes2026

Clinical Details of Low-Frequency Hearing Loss Observed in Autosomal Dominant

Hiromi Koizumi, Shin-Ya Nishio, Shin-Ichi Usami, Deafness Gene Study Consortium

Abstract read
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In one paragraph

Article in Genes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hiromi KoizumiDepartment of Otorhinolaryngology, Kyouai Hospital, Fujinomiya 418-0067, Japan.
Shin-Ya NishioDepartment of Hearing Implant Sciences, Shinshu University School of Medicine, Matsumoto 390-8621, Japan.ORCID 0000-0001-6640-2297
Shin-Ichi UsamiDepartment of Hearing Implant Sciences, Shinshu University School of Medicine, Matsumoto 390-8621, Japan.ORCID 0000-0002-5068-6122
Deafness Gene Study Consortium

Funding

Japan Agency for Medical Research and Development JP16kk0205010, JP18ek0109363, JP21ek0109542, JP24ek0109741Ministry of Health, Labor and Welfare of Japan H29-Nanchitou(Nan)-Ippan-031, 20FC10148, 23FC10149
6 · The paper itself

Abstract

BACKGROUND/

objectives

methodsA total of 18,475 Japanese patients with hearing loss were recruited. Targeted massively parallel sequencing of 158 deafness-related genes was performed, and individuals with variants related to

resultsAmong 18,475 hearing loss patients, we identified 60 patients from 44 unrelated families carrying five variants (p.[Asn140Lys; Glu1835Gln], p.Leu479Pro, p.Leu656Val, p.Gly660Arg, and p.Arg668His) for

conclusionsIn this study, we were able to clarify the specific features of

Indexed as

Myosin VIIaAdolescentAdultChildFemaleGenes, DominantHumansMaleMiddle AgedMutationPedigreeYoung AdultMYO7A protein, humanMyosin VIIaautosomal dominant hearing lossDFNA11low-frequency hearing lossMYO7Anext-generation sequencing

Identifiers

PMID41898848
PMCPMC13026303

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.