Evidence map›Paper›PMID 41898794›Full record

ArticleGenes2026

Gene Polymorphisms of

Johanna Teräsjärvi, Elina Tenhu, Manuel Leite Cruzeiro, Okko Savonius, Emilie Rugemalira, Qiushui He, Tuula Pelkonen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Johanna TeräsjärviInfection and Immunity, Institute of Biomedicine, University of Turku, 20520 Turku, Finland.
Elina TenhuInfection and Immunity, Institute of Biomedicine, University of Turku, 20520 Turku, Finland.
Manuel Leite CruzeiroHospital Pediátrico David Bernardino, Luanda Cx.P. 3067, Angola.
Okko SavoniusDepartment of Paediatrics, Helsinki University Hospital, University of Helsinki, Stenbäckinkatu 9, 00290 Helsinki, Finland.
Emilie RugemaliraDepartment of Paediatrics, Helsinki University Hospital, University of Helsinki, Stenbäckinkatu 9, 00290 Helsinki, Finland.
Qiushui HeInfection and Immunity, Institute of Biomedicine, University of Turku, 20520 Turku, Finland.
Tuula PelkonenHospital Pediátrico David Bernardino, Luanda Cx.P. 3067, Angola.ORCID 0000-0002-7688-9059

Funding

Sigrid Jusélius Foundation 26006199Tampere Tuberculosis Foundation 26006205
6 · The paper itself

Abstract

BACKGROUND/

objectivesBacterial meningitis is a severe disease with a fatality rate of 5-50%. It is mainly caused by

methodsThe study cohort consists of 190 bacterial meningitis patients aged 1 to 147 months from randomized clinical trials and 268 controls from Luanda, Angola. Polymorphisms of

resultsAt admission and during hospitalization, patients with pneumococcal meningitis carrying a variant (ins/del or del/del) of

conclusionsThis study suggests an association between coexisting infection and genetic variation in

Indexed as

Meningitis, BacterialMeningitis, PneumococcalPolymorphism, Single NucleotideToll-Like Receptor 10Toll-Like Receptor 2AngolaChildChild, PreschoolFemaleGenetic Predisposition to DiseaseHumansInfantMaleStreptococcus pneumoniaeTLR10 protein, humanTLR2 protein, humanToll-Like Receptor 10Toll-Like Receptor 2Angolabacterial meningitischildrenpneumococcal meningitisSNPStreptococcus pneumoniaeTLR10TLR2TLR2 subfamily

Identifiers

PMID41898794
PMCPMC13025349

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.