Evidence map›Paper›PMID 41898788›Full record

ArticleGenes2026

Analysis of the rs3807135, rs3757385 and rs3778754 Variants of the

Claudia A Tapia-Leyva, Fernando Valdez-Salazar, Luis A Jiménez-Del Río, Jorge R Padilla-Gutiérrez, José F Muñoz-Valle, Emmanuel Valdés-Alvarado

Abstract read
In one paragraph

Article in Genes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Claudia A Tapia-LeyvaInstituto de Investigación en Ciencias Biomédicas (IICB), Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Fernando Valdez-SalazarInstituto de Investigación en Ciencias Biomédicas (IICB), Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.ORCID 0009-0004-9116-4015
Luis A Jiménez-Del RíoInstituto de Investigación en Ciencias Biomédicas (IICB), Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.ORCID 0009-0003-0115-0174
Jorge R Padilla-GutiérrezInstituto de Investigación en Ciencias Biomédicas (IICB), Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.ORCID 0000-0002-0240-2797
José F Muñoz-ValleInstituto de Investigación en Ciencias Biomédicas (IICB), Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.ORCID 0000-0002-2272-9260
Emmanuel Valdés-AlvaradoInstituto de Investigación en Ciencias Biomédicas (IICB), Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.ORCID 0000-0001-6810-9203

Funding

Universidad de Guadalajara APPAC-VIII 2026
6 · The paper itself

Abstract

objectiveTo analyze the association between the

methodsAn analytical cross-sectional study was conducted including 374 individuals (153 patients with newly diagnosed melanoma and no previous treatment, and 221 controls). The melanoma group was matched to the reference group. Genotyping of the rs3807135 (T>C), rs3757385 (T>G), and rs3778754 (C>G) variants was performed using the allelic discrimination method with TaqMan

resultsNo statistically significant associations were identified between

conclusionsIn conclusion, the present study did not identify statistically significant associations between the

Indexed as

Interferon Regulatory FactorsMelanomaPolymorphism, Single NucleotideAdultAgedCase-Control StudiesCross-Sectional StudiesFemaleGene FrequencyGenetic Predisposition to DiseaseGenotypeHumansMaleMexicoMiddle AgedRNA, MessengerInterferon Regulatory FactorsIRF5 protein, humanRNA, MessengerexpresionIRF5melanomaMéxico populationvariants

Identifiers

PMID41898788
PMCPMC13026175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.