Molecular Insights into the Action Mechanism, Resistance Development, and Ecological Risks of Cyantraniliprole.

Jiabao Wu, Xiaohui Liu, Yuqing Peng, Jiguang Huang, Lijuan Zhou

Abstract readReview

In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiabao WuState Key Laboratory of Green Pesticides, South China Agricultural University, Guangzhou 510642, China.

Xiaohui LiuState Key Laboratory of Green Pesticides, South China Agricultural University, Guangzhou 510642, China.

Yuqing PengState Key Laboratory of Green Pesticides, South China Agricultural University, Guangzhou 510642, China.

Jiguang HuangState Key Laboratory of Green Pesticides, South China Agricultural University, Guangzhou 510642, China.

Lijuan ZhouState Key Laboratory of Green Pesticides, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0002-7720-4138

Funding

Guangdong Provincial Key R&D Program Project 2025B0202090001

6 · The paper itself

Abstract

Cyantraniliprole, a second-generation diamide insecticide, exhibits broad-spectrum efficacy against numerous insect pests due to its selective activation of insect ryanodine receptors (RyRs). This activation triggers uncontrolled calcium release from the sarcoplasmic reticulum, resulting in sustained muscle contraction, paralysis, and ultimately death. Its unique mode of action, which is different from that of organophosphates, carbamates, pyrethroids, and neonicotinoids, helps minimize cross-resistance, making it a valuable component of integrated pest management (IPM). However, continuous field use has led to the development of resistance, primarily mediated by target-site mutations within the RyR transmembrane domain (e.g.,

Indexed as

Insecticide ResistanceInsecticidesortho-AminobenzoatesPyrazolesAnimalsInsectaRyanodine Receptor Calcium Release ChannelcyantraniliproleInsecticidesortho-AminobenzoatesPyrazolesRyanodine Receptor Calcium Release Channelcyantraniliproleecotoxicologyenvironmental fatemolecular mechanismresistanceryanodine receptor

Identifiers

PMID41898757

DOI10.3390/ijms27062897

PMCPMC13026720

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.