Evidence map›Paper›PMID 41898602›Full record

ArticleInternational journal of molecular sciences2026

Tumor-Intrinsic PD-L1 Promotes Breast Cancer Proliferation Through Livin and Galectin-1-Mediated Regulation of SKP2 Expression.

Marwa Elfoly, Ayodele Alaiya, Amal A Al-Hazzani, Monther Al-Alwan, Hazem Ghebeh

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marwa ElfolyInnovation and Research, King Faisal Specialist Hospital & Research Centre, MBC 03, P.O. Box 3354, Riyadh 11211, Saudi Arabia.
Ayodele AlaiyaInnovation and Research, King Faisal Specialist Hospital & Research Centre, MBC 03, P.O. Box 3354, Riyadh 11211, Saudi Arabia.ORCID 0000-0003-2124-8550
Amal A Al-HazzaniDepartment of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2460, Riyadh 11451, Saudi Arabia.
Monther Al-AlwanInnovation and Research, King Faisal Specialist Hospital & Research Centre, MBC 03, P.O. Box 3354, Riyadh 11211, Saudi Arabia.ORCID 0000-0003-2150-5297
Hazem GhebehInnovation and Research, King Faisal Specialist Hospital & Research Centre, MBC 03, P.O. Box 3354, Riyadh 11211, Saudi Arabia.ORCID 0000-0002-3297-3996

Funding

King Faisal Specialist Hospital & Research Centre 2190002
6 · The paper itself

Abstract

Programmed Death-Ligand 1 (PD-L1) promotes tumor progression through several mechanisms, including its intrinsic effect on breast cancer cell proliferation via the S-Phase Kinase-Associated Protein 2 (SKP2)-p21

Indexed as

Adaptor Proteins, Signal TransducingB7-H1 AntigenBreast NeoplasmsGalectin 1Inhibitor of Apoptosis ProteinsNeoplasm ProteinsS-Phase Kinase-Associated ProteinsAnimalsCell Line, TumorCell ProliferationCyclin-Dependent Kinase Inhibitor p21Cyclin-Dependent Kinase Inhibitor p27FemaleGene Expression Regulation, NeoplasticHumansMiceAdaptor Proteins, Signal TransducingB7-H1 AntigenBIRC7 protein, humanCD274 protein, humanCyclin-Dependent Kinase Inhibitor p21Cyclin-Dependent Kinase Inhibitor p27Galectin 1Inhibitor of Apoptosis ProteinsNeoplasm ProteinsPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSKP2 protein, humanS-Phase Kinase-Associated ProteinsBIRC7Galactin-1LGALS1LivinPD-L1proliferationSKP2

Identifiers

PMID41898602
PMCPMC13026925

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.