Evidence map›Paper›PMID 41898510›Full record

ArticleInternational journal of molecular sciences2026

Anti-Inflammatory Potential of Novel Tethered Agonists of the Adhesion G Protein-Coupled Receptor F5.

Artur Wnorowski, Diana Pietrzak-Mitura, Akanksha Mudgal, Lorenzo Scrofani, Magdalena Strachowska, Piotr Draczkowski, Krzysztof Jóźwiak, Jakub Fichna, Damian Jacenik

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Artur WnorowskiDepartment of Biopharmacy, Faculty of Pharmacy, Medical University of Lublin, 20-059 Lublin, Poland.ORCID 0000-0002-2258-4225
Diana Pietrzak-MituraDepartment of Biopharmacy, Faculty of Pharmacy, Medical University of Lublin, 20-059 Lublin, Poland.
Akanksha MudgalDepartment of Biopharmacy, Faculty of Pharmacy, Medical University of Lublin, 20-059 Lublin, Poland.
Lorenzo ScrofaniDepartment of Biopharmacy, Faculty of Pharmacy, Medical University of Lublin, 20-059 Lublin, Poland.
Magdalena StrachowskaDepartment of Cytobiochemistry, Faculty of Biology and Environmental Protection, University of Lodz, 90-136 Lodz, Poland.ORCID 0000-0002-3100-1183
Piotr DraczkowskiDepartment of Synthesis and Chemical Technology of Pharmaceutical Substances, Faculty of Pharmacy, Medical University of Lublin, 20-059 Lublin, Poland.
Krzysztof JóźwiakDepartment of Biopharmacy, Faculty of Pharmacy, Medical University of Lublin, 20-059 Lublin, Poland.ORCID 0000-0001-6018-5092
Jakub FichnaDepartment of Biochemistry, Faculty of Medicine, Medical University of Lodz, 90-419 Lodz, Poland.ORCID 0000-0002-8443-4417
Damian JacenikDepartment of Cytobiochemistry, Faculty of Biology and Environmental Protection, University of Lodz, 90-136 Lodz, Poland.ORCID 0000-0003-4563-2303

Funding

National Science Centre 2019/32/C/NZ5/00064
6 · The paper itself

Abstract

The adhesion G protein-coupled receptor F5 (ADGRF5) has been implicated in modulating immune responses in cancer; however, its role in inflammatory bowel diseases (IBDs), particularly colitis, remains largely unexplored. In this study, we aimed to design and characterize novel peptide agonists derived from the ADGRF5

Indexed as

Anti-Inflammatory AgentsColitisPeptidesReceptors, G-Protein-CoupledAnimalsDisease Models, AnimalHumansMiceSignal TransductionAnti-Inflammatory AgentsPeptidesReceptors, G-Protein-CoupledADGRF5adhesion G protein-coupled receptor F5colitisGPR116immune responsetethered agonist

Identifiers

PMID41898510
PMCPMC13026237

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.