Myrtenol from Lavender Essential Oil Possesses Neuroprotective Effects and Promotes Neurite Outgrowth by Potentially Targeting TrkA and IGF-1R in PC12 Cells.

Ting Jiang, Lan Xiang, Jianhua Qi

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Ting JiangCollege of Pharmaceutical Sciences, Zhejiang University, Yu Hang Tang Road 866, Hangzhou 310058, China.

Lan XiangCollege of Pharmaceutical Sciences, Zhejiang University, Yu Hang Tang Road 866, Hangzhou 310058, China.ORCID 0000-0001-6595-2836

Jianhua QiCollege of Pharmaceutical Sciences, Zhejiang University, Yu Hang Tang Road 866, Hangzhou 310058, China.

Funding

National Key R&D Program of China 2022YFE0104000

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a prevalent chronic neurodegenerative disorder; the progression of this disease is driven by cellular determinants such as oxidative stress and dysregulated neurotrophic signaling. Lavender essential oil is traditionally used in aromatherapy for neuronal regulation and neuroprotection, suggesting its potential neuroprotective effects for chronic neurodegenerative disorders like AD. However, the key active constituents responsible for its benefits and the specific molecular pharmacological mechanisms remain unclear. In this study, we isolated myrtenol from lavender essential oil under the guidance of activity evaluation. Its neuroprotective effects were evaluated in PC12 cells via neurite outgrowth, anti-A

Indexed as

Neuronal OutgrowthNeuroprotective AgentsOils, VolatilePlant OilsReceptor, IGF Type 1Receptor, trkAAmyloid beta-PeptidesAnimalsBicyclic MonoterpenesHydrogen PeroxideLavandulaNeuritesOxidative StressPC12 CellsPeptide FragmentsProto-Oncogene Proteins c-aktAmyloid beta-Peptidesamyloid beta-protein (25-35)Bicyclic MonoterpenesHydrogen Peroxidelavender oilmyrtenolNeuroprotective AgentsOils, VolatilePeptide FragmentsPlant OilsProto-Oncogene Proteins c-aktReceptor, IGF Type 1Receptor, trkAAlzheimer’s diseasebioactive compoundscellular mechanismslavender essential oilnatural productsneurodegenerationneuroprotectionoxidative stress

Identifiers

PMID41898478

DOI10.3390/ijms27062615

PMCPMC13026966

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.