ArticleInternational journal of molecular sciences2026
Rational Design of Mn-APTES/1-Methylimidazole Nanozymes: Enhanced Laccase-like Activity at Near-Neutral pH for Environmental Remediation.
Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Natural laccases are a widely reported option for pollutant degradation; however, their widespread application is severely restricted by high production costs, limited storage stability, and rapid inactivation at the neutral pH typical of wastewater treatment plants. To overcome these limitations, we rationally designed manganese-based nanozymes (Mn-APTES/1MeIm) that mimic natural metal-histidine coordination within a protective siloxane network. Optimization via Response Surface Methodology produced two variants, Mn-APTES/1MeIm-6 and Mn-APTES/1MeIm-7, revealing distinct synthesis mechanisms: catalytic activity at pH 6 is driven by synthesis temperature, whereas activity at pH 7 is controlled by the APTES:1MeIm molar ratio. TEM and XRD analysis confirmed a delaminated aminoclay architecture composed of electron-transparent nanosheets, while FTIR verified Mn-N coordination through characteristic blue shifts. The optimized nanozymes retained robust activity, exhibiting maximum reaction velocities of 4.331 µM min
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.