ArticleBiomedicines2026
Primary Cilia Are Required for Efficient BMP Signaling in Traumatic Heterotopic Ossification.
Xinyuan Yuan, Saman Toutounchi, Susan F Law, David Achudhan, Abhishek Chandra, Kai He, Yingshu Cao, Jinghua Hu, Robert J Pignolo, Haitao Wang
Abstract read
In one paragraphArticle in Biomedicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
10 authors.
Xinyuan YuanDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
Saman ToutounchiDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
Susan F LawDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
David AchudhanDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0002-2917-0578 Abhishek ChandraDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0001-9423-9669 Kai HeDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Yingshu CaoDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Jinghua HuDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Robert J PignoloDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
Haitao WangDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0003-2340-0739 Funding
Molecular dissection of the ciliary gateR01DK099160 · NIDDK · MAYO CLINIC ROCHESTER · PI Jinghua Hu · 2014 to 2026
$4.0MThe essential roles of primary cilia in heterotopic ossificationR01AR081318 · NIAMS · MAYO CLINIC ROCHESTER · PI WANG, HAITAO · 2023 to 2025
$2.1MA novel cilium-to-nucleus axis promotes cellular senescenceR01AG076469 · NIA · MAYO CLINIC ROCHESTER · PI Jinghua Hu · 2022 to 2026
$1.6MNIAMS NIH HHS R01 AR081318NIA NIH HHS R01 AG076469NIDDK NIH HHS R01 DK099160NIH HHS 1R01AR081318-01Robert and Arlene Kogod Professorship N/Athe International Fibrodysplasia Ossificans Progressiva Association (IFOPA) N/A
6 · The paper itselfAbstract
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Indexed as
bone morphogenetic protein (BMP) signalingprimary ciliatenocytestraumatic heterotopic ossification
Identifiers
PMID41898356
PMCPMC13023636
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