Evidence map›Paper›PMID 41898227›Full record

ArticleBiomedicines2026

Computational Pharmacodynamic Analysis of Cyclopeptides Derived from c[Trp-Phe-D-Pro-Phe] (CJ-15,208), an Unusual Class of Mixed μ/k-Opioid Receptor Ligands Lacking the Traditional Pharmacophores.

Marco Francescato, Hang Liao, Lorenzo Cavina, Andrea Bedini, Luca Gentilucci

Abstract read
In one paragraph

Article in Biomedicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marco FrancescatoDepartment of Chemistry "G. Ciamician", University of Bologna, Plesso Navile-Ue4, via Gobetti 85, 40129 Bologna, Italy.ORCID 0009-0008-1307-5729
Hang LiaoDepartment of Chemistry "G. Ciamician", University of Bologna, Plesso Navile-Ue4, via Gobetti 85, 40129 Bologna, Italy.ORCID 0009-0001-1259-8412
Lorenzo CavinaDepartment of Chemistry "G. Ciamician", University of Bologna, Plesso Navile-Ue4, via Gobetti 85, 40129 Bologna, Italy.ORCID 0000-0001-6700-1559
Andrea BediniDepartment of Pharmacy and Biotechnology, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0001-9607-9195
Luca GentilucciDepartment of Chemistry "G. Ciamician", University of Bologna, Plesso Navile-Ue4, via Gobetti 85, 40129 Bologna, Italy.ORCID 0000-0001-9134-3161

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

atypical agonistCJ-15,208conformational analysiscyclotetrapeptidemolecular dockingopioid receptor

Identifiers

PMID41898227
PMCPMC13024161

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.