Evidence map›Paper›PMID 41897953›Full record

ArticleAnimals : an open access journal from MDPI2026

Intestinal Development in Wuzhishan Pigs at Different Growth Phases: Insights from Microbiome and Metabolomics.

Jing Fan, Xinyu Xue, Haojie Zhang, Feng Wang, Zhe Chao, Limin Wei, Hailong Liu, Yuwei Ren, Ruiping Sun

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jing FanKey Laboratory of Tropical Animal Breeding and Epidemic Disease Research, Institute of Animal Husbandry and Veterinary Research, Hainan Academy of Agricultural Sciences, Haikou 571100, China.ORCID 0000-0001-5925-6770
Xinyu XueKey Laboratory of Tropical Animal Breeding and Epidemic Disease Research, Institute of Animal Husbandry and Veterinary Research, Hainan Academy of Agricultural Sciences, Haikou 571100, China.
Haojie ZhangCollege of Animal Science and Technology, Guangxi University, Nanning 530005, China.
Feng WangKey Laboratory of Tropical Animal Breeding and Epidemic Disease Research, Institute of Animal Husbandry and Veterinary Research, Hainan Academy of Agricultural Sciences, Haikou 571100, China.
Zhe ChaoKey Laboratory of Tropical Animal Breeding and Epidemic Disease Research, Institute of Animal Husbandry and Veterinary Research, Hainan Academy of Agricultural Sciences, Haikou 571100, China.
Limin WeiKey Laboratory of Tropical Animal Breeding and Epidemic Disease Research, Institute of Animal Husbandry and Veterinary Research, Hainan Academy of Agricultural Sciences, Haikou 571100, China.
Hailong LiuKey Laboratory of Tropical Animal Breeding and Epidemic Disease Research, Institute of Animal Husbandry and Veterinary Research, Hainan Academy of Agricultural Sciences, Haikou 571100, China.
Yuwei RenKey Laboratory of Tropical Animal Breeding and Epidemic Disease Research, Institute of Animal Husbandry and Veterinary Research, Hainan Academy of Agricultural Sciences, Haikou 571100, China.
Ruiping SunKey Laboratory of Tropical Animal Breeding and Epidemic Disease Research, Institute of Animal Husbandry and Veterinary Research, Hainan Academy of Agricultural Sciences, Haikou 571100, China.

Funding

Hainan Local Pig Agricultural Research System HNARS-02-Z01National Natural Science Foundation of China U22A20508The 2020 Research Program of Sanya Yazhou Bay Science and Technology City 202002011The National Key R&D Program of China 2021YFF0702804
6 · The paper itself

Abstract

Wuzhishan pigs are a typical Chinese indigenous miniature pig breed, with thin skin and high amino acid content in muscle; slow weight gain and long feeding phases limit their value. As the primary digestive and absorptive organ, the intestine is crucial for growth, yet current studies on its development are limited. This study aimed to investigate intestinal physiological differences in Wuzhishan pigs across four phases (pre-weaning: 7, 14 days; weaning: 35, 38, 45 days; fattening: 70, 100 days; maturity: 180, 240 days) by evaluating intestinal morphology, digestive enzyme activity, gut microbiota diversity via 16S rRNA gene sequencing, and metabolite characteristics via metabolomic analysis. Results showed poor intestinal morphology and enzyme activity during weaning, significant ileal and colonic microbial diversity differences across phases, increased beneficial bacteria with age, and enriched opportunistic pathogens (

Indexed as

developmental phasesintestinal microbiotaintestinal morphologymetabolitesWuzhishan pig

Identifiers

PMID41897953
PMCPMC13023668

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.