Understanding Acceptance of Genome-Edited Crops and Foods: The Role of Trust, Attitudes, and Perceived Literacy in Italy.

Genome-editing (GE) techniques are gaining relevance in the agri-food system for their potential to enhance crop resilience and sustainability, raising questions about consumer acceptance and responsible innovation. Understanding public willingness to buy (WTB) GE foods is therefore essential. While trust in science is often cited as a key driver, its effects are not straightforward. This study examines mechanisms linking trust in science to WTB GE foods, testing the mediating role of attitudes and the moderating role of perceived literacy. A cross-sectional online survey was conducted with a representative sample of Italian adults. Using structural equation modelling, we tested three models: a mediation model, a model including a direct path between trust and WTB, and a moderated model incorporating perceived literacy. Trust predicted more favourable attitudes toward GE, and attitudes were strongly associated with WTB. However, when controlling for attitudes, the direct effect of trust on WTB was negative. Perceived literacy significantly moderated this relationship: higher perceived literacy strengthened the negative trust-WTB association. Overall, generalized trust in science is not sufficient for public acceptance of GE crops and foods. Communication strategies should move beyond trust-building and foster informed, critically engaged consumers.