ReviewDiagnostics (Basel, Switzerland)2026
Molecular and Microenvironmental Mechanisms of Malignant Transformation in Benign Salivary Gland Tumors: Implications for Oral Squamous Cell Carcinoma.
Review in Diagnostics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Diagnosis and Management in Oral and Maxillofacial Surgery.Diagnostics (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malignant transformation of benign salivary gland tumors represents a critical biological process that provides valuable insights into head and neck carcinogenesis, with potential implications for oral squamous cell carcinoma (OSCC). Understanding the molecular, epigenetic, and microenvironmental mechanisms underlying this transition is essential for improving early diagnosis, risk stratification, and personalized management strategies. This study presents a comprehensive narrative review of the current literature focusing on benign salivary gland tumors with malignant potential, particularly pleomorphic adenoma and carcinoma ex pleomorphic adenoma, emphasizing molecular alterations, angiogenesis, and tumor microenvironment dynamics. A structured literature search was conducted across major biomedical databases, including PubMed and Scopus, selecting studies that addressed genetic rearrangements, epigenetic modifications, histopathological features, and clinical connections of malignant transformation. The findings highlight recurrent genetic alterations such as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.