Heterologous Production of 2,2'-Dihydroxy Derivatives of Astaxanthin and Adonirubin in

Rika Sekine, Miho Takemura, Misato Nagamori, Norihiko Misawa, Kazutoshi Shindo

Abstract read

In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rika SekineDepartment of Food and Nutrition, Japan Women's University, 2-8-1 Mejirodai, Bunkyo-ku, Tokyo 112-8681, Japan.

Miho TakemuraResearch Institute for Bioresources and Biotechnology, Ishikawa Prefectural University, 1-308 Suematsu, Nonoichi-shi 921-8836, Japan.ORCID 0000-0001-5211-004X

Misato NagamoriDepartment of Food and Nutrition, Japan Women's University, 2-8-1 Mejirodai, Bunkyo-ku, Tokyo 112-8681, Japan.

Norihiko MisawaResearch Institute for Bioresources and Biotechnology, Ishikawa Prefectural University, 1-308 Suematsu, Nonoichi-shi 921-8836, Japan.ORCID 0000-0003-1373-0769

Kazutoshi ShindoDepartment of Food and Nutrition, Japan Women's University, 2-8-1 Mejirodai, Bunkyo-ku, Tokyo 112-8681, Japan.ORCID 0000-0002-9281-0822

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Astaxanthin is a prominent carotenoid with strong antioxidant activity due to its 13 conjugated double bonds and its 3,3'-hydroxy groups adjacent to its 4,4'-carbonyl groups. This red pigment is utilized as a food additive and nutritional supplement, and it also has applications in cosmetics. But the extremely low water solubility of astaxanthin limits its broader commercial application. In order to decrease the hydrophobic property of astaxanthin, we produced 2,2'-dihydroxy derivatives of astaxanthin and its intermediate adonirubin, (2

Indexed as

2,2′-dihydroxyadonirubin2,2′-dihydroxyastaxanthinantioxidant activityEscherichia coli

Identifiers

PMID41897473

DOI10.3390/antiox15030327

PMCPMC13023446

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.