Evidence map›Paper›PMID 41897469›Full record

ArticleAntioxidants (Basel, Switzerland)2026

Apigenin Prevents Ovarian Aging by Regulating Ca

Wanyue Gao, Jing Dong, Yingyu Xiao, Xiangyu Cai, Zhaoyu Yang, Weidong Zeng, Caiqiao Zhang, Yuling Mi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Mitochondrial CaFrontiers in cell and developmental biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wanyue GaoDepartment of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0009-0003-8995-3595
Jing DongDepartment of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Yingyu XiaoDepartment of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Xiangyu CaiDepartment of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Zhaoyu YangDepartment of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0009-0001-8401-5087
Weidong ZengDepartment of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Caiqiao ZhangDepartment of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-3519-9457
Yuling MiDepartment of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.

Funding

National Natural Science Foundation of China 32372952, 32272950
6 · The paper itself

Abstract

The sustainability of egg production in the poultry industry is frequently challenged by the progressive decline in ovarian function as laying chickens age. A primary driver of this reproductive transition is the functional deterioration of small white follicles (SWFs), which constitute the vital pre-hierarchical follicular reserve necessary for sustained egg production. However, the molecular mechanisms underlying age-associated SWF atresia remain poorly understood. In this study, we investigated the protective efficacy of apigenin (AP), a natural bioactive flavonoid, in mitigating follicular senescence by targeting calcium ion (Ca

Indexed as

apigeninCa2+ homeostasischickensERSovarian aging

Identifiers

PMID41897469
PMCPMC13024370

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.