Evidence map›Paper›PMID 41897433›Full record

ArticleAntioxidants (Basel, Switzerland)2026

THC and CBD Induce Heme Oxygenase-1-Dependent Cell Death and Trigger Mitochondrial Dysfunction in Human Melanoma and Cutaneous Squamous Cell Carcinoma Cells.

Elisabeth Thamm, Felix Wittig, Bianca Hamann, Franziska Wendt, Steffen Emmert, Marcus Frank, Burkhard Hinz

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elisabeth ThammInstitute of Pharmacology and Toxicology, Rostock University Medical Center, 18057 Rostock, Germany.
Felix WittigInstitute of Pharmacology and Toxicology, Rostock University Medical Center, 18057 Rostock, Germany.
Bianca HamannInstitute of Pharmacology and Toxicology, Rostock University Medical Center, 18057 Rostock, Germany.ORCID 0009-0007-3248-8783
Franziska WendtInstitute of Pharmacology and Toxicology, Rostock University Medical Center, 18057 Rostock, Germany.
Steffen EmmertClinic and Policlinic for Dermatology, Rostock University Medical Center, 18057 Rostock, Germany.ORCID 0000-0001-5630-4204
Marcus FrankElectron Microscopy Center, Rostock University Medical Center, 18057 Rostock, Germany.ORCID 0000-0002-2517-4440
Burkhard HinzInstitute of Pharmacology and Toxicology, Rostock University Medical Center, 18057 Rostock, Germany.ORCID 0000-0002-2529-0732

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the search for new therapeutic strategies for the treatment of skin cancer, cannabinoids have become the focus of scientific interest. The present study investigated the effects of the phytocannabinoids Δ

Indexed as

cannabinoidscell deathcutaneous squamous cell carcinoma cellsheme oxygenase-1melanoma cellsmitochondriaoxygen consumption raterespiratory chain complex proteinsskin cancer

Identifiers

PMID41897433
PMCPMC13024539

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.