ReviewBiomolecules2026
Attachment Theory: Novel Clinical and Molecular Insights.
Review in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Early-life adversity (ELA) disrupts brain development and is linked to poor health outcomes across species, including humans and rodents. A growing body of work suggests that impaired attachment to a caregiver-arising from erratic, neglectful, or abusive parenting-mediates a substantial portion of ELA's long-term effects. Despite the conceptual and clinical appeal of this idea, the neural mechanisms by which ELA disrupts attachment and how altered attachment in turn produces diverse psychiatric and medical sequelae remain incompletely understood. In this review, we synthesize recent randomized controlled trials showing that strengthening caregiver-child attachment can ameliorate a broad range of ELA-related outcomes. We also highlight key animal studies that illuminate the biology of attachment and outline critical priorities for future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.