Evidence map›Paper›PMID 41897361›Full record

ArticleBiomolecules2026

Serine Protease HtrA2 from Halophilic Archeon

Aslıhan Kurt-Kızıldoğan, Ömer Konuksever, Özlem Yavuz, Çiğdem Otur, Büşra Abanoz-Seçgin, Sezer Okay

Abstract read
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Partial purification and characterization of an extracellular cold-active protease from Flavobacterium azizsancarii, a novel Antarctic isolate.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aslıhan Kurt-KızıldoğanDepartment of Agricultural Biotechnology, Faculty of Agriculture, Ondokuz Mayıs University, Samsun 55139, Türkiye.ORCID 0000-0002-9323-0993
Ömer KonukseverDepartment of Agricultural Biotechnology, Faculty of Agriculture, Ondokuz Mayıs University, Samsun 55139, Türkiye.ORCID 0000-0001-6613-793X
Özlem YavuzDepartment of Agricultural Biotechnology, Faculty of Agriculture, Ondokuz Mayıs University, Samsun 55139, Türkiye.ORCID 0009-0000-3867-2396
Çiğdem OturDepartment of Agricultural Biotechnology, Faculty of Agriculture, Ondokuz Mayıs University, Samsun 55139, Türkiye.ORCID 0000-0003-3337-7990
Büşra Abanoz-SeçginDepartment of Agricultural Biotechnology, Faculty of Agriculture, Ondokuz Mayıs University, Samsun 55139, Türkiye.ORCID 0000-0002-2371-2022
Sezer OkayDepartment of Vaccine Technology, Vaccine Institute, Hacettepe University, Ankara 06230, Türkiye.ORCID 0000-0003-0355-6672

Funding

Ondokuz Mayıs University PYO.ZRT.1901.21.006
6 · The paper itself

Abstract

Halophilic proteases are valuable in industrial applications due to their resistance to harsh conditions. HtrA2 serine protease is widely distributed and conserved among eukaryotes and prokaryotes. However, HtrA2 proteases from archaea have been poorly characterized. In this study,

Indexed as

Archaeal ProteinsHaloarculaSerine ProteasesAmino Acid SequenceCloning, MolecularEnzyme StabilityEscherichia coliHydrogen-Ion ConcentrationHydroxybutyratesNanoparticlesPolyhydroxybutyratesRecombinant ProteinsSerine EndopeptidasesTemperatureArchaeal ProteinsHydroxybutyratespolyhydroxybutyratePolyhydroxybutyratesRecombinant ProteinsSerine EndopeptidasesSerine Proteasesenzyme immobilizationhaloarchaeahalophilic proteasePHB

Identifiers

PMID41897361
PMCPMC13024417

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.