Evidence map›Paper›PMID 41897332›Full record

ReviewBiomolecules2026

Synthetic Modulators of the Vitamin D Receptor: From Structural Innovation to Disease-Specific Applications.

Tram Thi-Ngoc Nguyen, Tomohiro Kurokawa, Yoshiaki Kanemoto, Takahiro Sawada, Shigeaki Kato

Abstract readReview
In one paragraph

Review in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tram Thi-Ngoc NguyenDepartment of Pharmacy, Iryo Sosei University, Iino, Chuo-dai, Iwaki 970-8551, Fukushima, Japan.
Tomohiro KurokawaDepartment of Pharmacy, Iryo Sosei University, Iino, Chuo-dai, Iwaki 970-8551, Fukushima, Japan.ORCID 0000-0002-7932-8724
Yoshiaki KanemotoDepartment of Pharmacy, Iryo Sosei University, Iino, Chuo-dai, Iwaki 970-8551, Fukushima, Japan.
Takahiro SawadaDepartment of Pharmacy, Iryo Sosei University, Iino, Chuo-dai, Iwaki 970-8551, Fukushima, Japan.
Shigeaki KatoDepartment of Pharmacy, Iryo Sosei University, Iino, Chuo-dai, Iwaki 970-8551, Fukushima, Japan.ORCID 0000-0002-5564-1695

Funding

Japan Society for the Promotion of Science KAKENHI #23K15502
6 · The paper itself

Abstract

Vitamin D signaling via the vitamin D receptor (VDR) regulates calcium-phosphate homeostasis and extensive gene programs controlling cell proliferation, differentiation, immune tone, and metabolism. However, systemic use of the natural agonist 1α,25-dihydroxyvitamin D

Indexed as

Receptors, CalcitriolAnimalsCalcitriolHumansLigandsSignal TransductionVitamin DCalcitriolLigandsReceptors, CalcitriolVitamin Dhelix-12 conformational changehypercalcemialigand-dependent transcriptionselective nuclear receptor modulatorssynthetic vitamin D analogsVitamin D Receptor (VDR)

Identifiers

PMID41897332
PMCPMC13023678

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.