Evidence map›Paper›PMID 41897322›Full record

ReviewBiomolecules2026

Establishment and Maintenance of Repressed Chromatin States on Dosage-Compensated Sex Chromosomes.

Joshua Eduful, Lily LeSarge, Györgyi Csankovszki

Abstract readReview
In one paragraph

Review in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joshua EdufulDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0009-0003-7984-1290
Lily LeSargeDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Györgyi CsankovszkiDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0001-5918-034X

Funding

The gene regulatory functions of condensinR35GM149543 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Gyorgyi Csankovszki · 2023 to 2026
$1.8M
NIGMS NIH HHS R35 GM149543
6 · The paper itself

Abstract

Sex chromosome imbalance is a genetic challenge in species with unequal X-chromosome numbers. Organisms have developed distinct strategies to control this imbalance through a process called dosage compensation. These strategies include X-chromosome inactivation in mammals mediated by the XIST long noncoding RNA and proteins recruited by XIST, and X-linked hypertranscription in male

Indexed as

ChromatinDosage Compensation, GeneticSex ChromosomesAdenosine TriphosphatasesAnimalsCaenorhabditis elegansDNA-Binding ProteinsHumansMaleMultiprotein ComplexesRNA, Long NoncodingX ChromosomeX Chromosome InactivationAdenosine TriphosphatasesChromatincondensin complexesDNA-Binding ProteinsMultiprotein ComplexesRNA, Long NoncodingXIST non-coding RNAcondensindosage compensationepigeneticsmaintenanceXIST

Identifiers

PMID41897322
PMCPMC13023952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.