Evidence map›Paper›PMID 41897315›Full record

ArticleBiomolecules2026

Chrysotoxine Attenuates Key Atherogenic Processes via Antioxidant, Anti-Inflammatory, and COX-Dependent Antiplatelet Mechanisms.

Fozia Rustamani, Hla Nu Swe, Su Wutyi Thant, Jeeradej Moonrut, Boonchoo Sritularak, Ponlapat Rojnuckarin, Nonthaneth Nalinratana, Rataya Luechapudiporn

Abstract read
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fozia RustamaniPharmaceutical Sciences and Technology Program, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0002-5940-9463
Hla Nu SwePharmaceutical Sciences and Technology Program, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0003-2030-9008
Su Wutyi ThantPharmaceutical Sciences and Technology Program, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0002-4637-461X
Jeeradej MoonrutInterdisciplinary Program in Pharmacology, Graduate School, Chulalongkorn University, Bangkok 10330, Thailand.
Boonchoo SritularakDepartment of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0001-8352-4122
Ponlapat RojnuckarinDepartment of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0001-7912-1996
Nonthaneth NalinratanaCenter of Excellence in Natural Products for Ageing and Chronic Diseases, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Rataya LuechapudipornCenter of Excellence in Natural Products for Ageing and Chronic Diseases, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0002-2327-5766

Funding

90th Anniversary of Chulalongkorn University Scholarship under Ratchadaphisek Somphot Fund GCUGR1125681015DThailand Science Research and Innovation Fund Chulalongkorn University 196866
6 · The paper itself

Abstract

Atherosclerosis is a complex vascular disorder driven by oxidative stress, inflammation, and platelet activation. Agents capable of targeting multiple atherogenic pathways may provide improved therapeutic benefits. In this study, we evaluated the anti-atherogenic effects of chrysotoxine, a bibenzyl compound isolated from

Indexed as

Anti-Inflammatory AgentsAntioxidantsAtherosclerosisPlatelet Aggregation InhibitorsCyclooxygenase 1Cyclooxygenase 2HumansLipid PeroxidationLipoproteins, LDLMolecular Docking SimulationMonocytesOxidative StressPlatelet AggregationAnti-Inflammatory AgentsAntioxidantsCyclooxygenase 1Cyclooxygenase 2Lipoproteins, LDLPlatelet Aggregation Inhibitorsatherosclerosischrysotoxinecyclooxygenase (COX)LDL oxidationplatelet activationvascular inflammation

Identifiers

PMID41897315
PMCPMC13024289

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.