Evidence map›Paper›PMID 41897285›Full record

ArticleBiomolecules2026

New 1,2,3-Triazole and Dipyridothiazine Hybrids-Synthesis, Analysis, Cytotoxicity and Molecular Docking.

Emilia Martula, Weronika Bagrowska, Paulina Strzyga-Łach, Marta Struga, Małgorzata Latocha, Dariusz Kuśmierz, Małgorzata Jeleń, Beata Morak-Młodawska

Abstract read
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In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Emilia MartulaDepartment of Organic Chemistry, Faculty of Pharmaceutical Sciences, The Medical University of Silesia, Jagiellońska 4, 41-200 Sosnowiec, Poland.
Weronika BagrowskaTunneling Group, Biotechnology Centre, Silesian University of Technology, Krzywoustego 8, 44-100 Gliwice, Poland.ORCID 0000-0003-1749-8514
Paulina Strzyga-ŁachDepartment of Biochemistry, Medical University of Warsaw, 02-097 Warsaw, Poland.ORCID 0000-0003-1830-2210
Marta StrugaDepartment of Biochemistry, Medical University of Warsaw, 02-097 Warsaw, Poland.ORCID 0000-0002-0181-3607
Małgorzata LatochaDepartment of Cell Biology, Faculty of Pharmaceutical Sciences, The Medical University of Silesia, Jedności 8, 41-200 Sosnowiec, Poland.ORCID 0000-0003-4109-2629
Dariusz KuśmierzDepartment of Cell Biology, Faculty of Pharmaceutical Sciences, The Medical University of Silesia, Jedności 8, 41-200 Sosnowiec, Poland.
Małgorzata JeleńDepartment of Organic Chemistry, Faculty of Pharmaceutical Sciences, The Medical University of Silesia, Jagiellońska 4, 41-200 Sosnowiec, Poland.ORCID 0000-0002-4144-990X
Beata Morak-MłodawskaDepartment of Organic Chemistry, Faculty of Pharmaceutical Sciences, The Medical University of Silesia, Jagiellońska 4, 41-200 Sosnowiec, Poland.ORCID 0000-0001-5389-1079

Funding

The Medical University of Silesia BNW-2-051/K/4/F, BNW-1-048/K/5/F, BNW-1-105/K/4/F
6 · The paper itself

Abstract

Epigenetic and stress-response pathways play central roles in cancer progression and represent attractive therapeutic targets. In this study, a series of dipyridothiazine-1,2,3-triazole hybrids bearing

Indexed as

Antineoplastic AgentsMolecular Docking SimulationTriazolesApoptosisCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorHumansAntineoplastic AgentsTriazolesanticancer actioncytotoxicitydiazaphenothiazinegene expression analysisHDAC6

Identifiers

PMID41897285
PMCPMC13023989

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.