ArticleChildren (Basel, Switzerland)2026
Early Prediction of Acute Kidney Injury Using the Furosemide Stress Test in Pediatric Cardiac Surgery Patients.
Article in Children (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionWe evaluated the furosemide stress test as an early predictor of acute kidney injury following pediatric cardiac surgery, in comparison with the Kidney Disease: Improving Global Outcomes (KDIGO) diagnostic criteria. MATERIALS AND
methodsThis single-centre retrospective study evaluated pediatric patients who underwent open cardiac surgery between March 2019 and September 2024 at Koç University Hospital. The evaluation included pre-operative, intra-operative, and postoperative variables; a two-hour assessment of urinary response to the first dose of furosemide upon admission to the intensive care unit; and rates of acute kidney injury.
resultsA total of 254 patients were included, and 53 patients (20.8%) developed acute kidney injury according to KDIGO criteria. The mean furosemide stress test response was 9.86 ± 5.84 (median: 9.10) mL/kg/h in the non-AKI group and was significantly lower in the AKI group at 5.07 ± 4.73 (median: 3.33) mL/kg/h (
conclusionsThe findings support the potential clinical utility of the furosemide stress test in the early stages after pediatric cardiac surgery to predict acute kidney injury.
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