Evidence map›Paper›PMID 41897024›Full record

ArticleChildren (Basel, Switzerland)2026

Salpingitis in Non-Sexually Active Girls: Clinical Spectrum and Diagnostic Clues from a Pediatric Cohort.

Matteo Cerutti, Marta Verzieri, Lisa Gamalero, Erica Bencini, Ilaria Brizzi, Gaia Varriale, Stefano Stagi, Teresa Giani

Abstract read
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Article in Children (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Matteo CeruttiPediatric Diabetology and Endocrinology Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.
Marta VerzieriDepartment of Health Sciences, University of Florence, 50139 Florence, Italy.
Lisa GamaleroPaediatric Division, ULSS2 Marca Trevigiana, Conegliano Hospital, 31015 Conegliano, Italy.
Erica BenciniPediatric Gynecology Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.
Ilaria BrizziDepartment of Pediatrics, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.
Gaia VarrialePediatric Diabetology and Endocrinology Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.ORCID 0000-0002-3728-0494
Stefano StagiPediatric Diabetology and Endocrinology Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.
Teresa GianiReumatology Unit, Department of Pediatrics, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.ORCID 0000-0001-9292-7601

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPediatric salpingitis is rare and often underrecognized, especially in non-sexually active girls in whom symptoms are non-specific and sexually transmitted infections are absent. Delayed diagnosis may increase the risk of complications. We aimed to characterize the clinical presentation, diagnostic features, management, and outcomes of pediatric salpingitis and to identify predisposing factors in non-sexually active pediatric patients.

methodsWe retrospectively reviewed pediatric cases of radiologically or surgically confirmed salpingitis at a tertiary children's hospital (2000-2025) and conducted a narrative review of published pediatric cases.

resultsTen non-sexually active girls were included (median age 12.8 years). Abdominal pain was the most common symptom (80%), followed by fever and gastrointestinal complaints (50% and 30%, respectively); two patients (20%) were asymptomatic. Hydrosalpinx or pyosalpinx was detected on ultrasound in 80%. A causative organism was identified in 30%, predominantly enteric or anaerobic flora. All patients received broad-spectrum intravenous antibiotics; half required procedural or surgical intervention. Clinical outcomes were favorable in all cases. The literature review identified 56 additional non-sexually active girls, most of whom were postmenarchal. Abdominal pain was the predominant presentation, and gastrointestinal or anatomical predisposing factors were common.

conclusionsNon-sexually transmitted salpingitis is an uncommon but clinically relevant condition in children. Its atypical and often subtle presentation in non-sexually active girls warrants heightened clinical awareness. Early imaging and attention to gastrointestinal or postsurgical antecedents can facilitate timely diagnosis. Further multicenter studies are needed to establish diagnostic criteria and clarify long-term reproductive outcomes.

Indexed as

hydrosalpinxpediatricpyosalpinxsalpingitistubo-ovarian abscess

Identifiers

PMID41897024
PMCPMC13025358

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