ArticleBMC chemistry2026
Development of a novel voltammetric method for revefenacin determination using modified electrodes in pharmaceutical and biological matrices.
Article in BMC chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
Revefenacin (REV) is an inhalation solution used for management of Chronic Obstructive Pulmonary Disease (COPD) in the USA, this is single medication that is an approved bronchodilator delivered by nebulization with a once-daily frequency. Even though the crucial necessity of quality control in pharmaceutical manufacturing, no officially recognized methods exist for REV determination in biological samples. A sensitive, economical, simple and efficient electrochemical procedure using carbon paste modified with nanostructured zinc oxide electrode (ZnO-NPs/CPE) was designed for remarkably trace analysis of REV. It was demonstrated that the (ZnO-NPs/CPE) electrode in the Britton-Robinson buffer adjusted to pH 4.0 with the anionic surfactant sodium dodecyl sulfate (SDS), the electrochemical oxidation of REV was significantly enhanced. Under optimal conditions, the REV electrochemical process was irreversible and adsorption-mediated. Scanning Electron Microscopy (SEM) and Energy-Dispersive X-ray Spectroscopy (EDX) were utilized to characterize the morphology of the modified electrode. Under optimal experimental conditions, the analytical results showed direct relationship responses in the range of 0.19-2.0 µg mL
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