Evidence map›Paper›PMID 41896972›Full record

Observational studyScandinavian journal of trauma, resuscitation and emergency medicine2026

BMI is independently associated with ARDS, sepsis and multiorgan failure after major trauma-results of a high-volume retrospective observational cohort study.

B Erdle, J Mangold, J Kalbhenn, T D Diallo, F C Wagner, J Maier, H Schmal, N Mühlenfeld

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Scandinavian journal of trauma, resuscitation and emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

B ErdleDepartment of Orthopedics and Trauma Surgery, Medical Centre - Albert‑Ludwig's University Freiburg, Faculty of Medicine, Albert‑Ludwig's University of Freiburg, Hugstetter Straße 55, Freiburg, D‑79106, Germany. benjamin.erdle@uniklinik-freiburg.de.ORCID http://orcid.org/0000-0001-8524-6779
J MangoldDepartment of Orthopedics and Trauma Surgery, Medical Centre - Albert‑Ludwig's University Freiburg, Faculty of Medicine, Albert‑Ludwig's University of Freiburg, Hugstetter Straße 55, Freiburg, D‑79106, Germany.
J KalbhennDepartment of Anesthesiology and Critical Care, Medical Centre - Albert‑Ludwig's University Freiburg, Faculty of Medicine, Albert‑Ludwig's University of Freiburg, Freiburg, Germany.
T D DialloDepartment of Diagnostic and Interventional Radiology, Medical Centre - Albert‑Ludwig's University Freiburg, Faculty of Medicine, Albert‑Ludwig's University of Freiburg, Freiburg, Germany.
F C WagnerDepartment of Orthopedics and Trauma Surgery, Medical Centre - Albert‑Ludwig's University Freiburg, Faculty of Medicine, Albert‑Ludwig's University of Freiburg, Hugstetter Straße 55, Freiburg, D‑79106, Germany.
J MaierDepartment of Orthopedics and Trauma Surgery, Medical Centre - Albert‑Ludwig's University Freiburg, Faculty of Medicine, Albert‑Ludwig's University of Freiburg, Hugstetter Straße 55, Freiburg, D‑79106, Germany.
H SchmalDepartment of Orthopedics and Trauma Surgery, Medical Centre - Albert‑Ludwig's University Freiburg, Faculty of Medicine, Albert‑Ludwig's University of Freiburg, Hugstetter Straße 55, Freiburg, D‑79106, Germany.
N MühlenfeldDepartment of Orthopedics and Trauma Surgery, Medical Centre - Albert‑Ludwig's University Freiburg, Faculty of Medicine, Albert‑Ludwig's University of Freiburg, Hugstetter Straße 55, Freiburg, D‑79106, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity is increasingly prevalent among trauma patients and has been proposed to influence post-injury inflammatory responses and organ dysfunction. However, evidence on the independent effect of body mass index (BMI) on in-hospital complications after major trauma remains conflicting. This study aimed to determine whether BMI is an independent predictor of specific adverse clinical outcomes in a large cohort of adult trauma patients.

methodsThis retrospective cohort study analyzed associations between BMI and adverse clinical outcomes (ARDS, pneumonia, sepsis, multiorgan failure (MOF) and mortality) among adult trauma patients at a German level-I trauma center between 2018 and 2024. Inclusion criteria were trauma leading to an Injury Severity Score (ISS) ≥ 9 and/or admission to the intensive care unit. Multivariable logistic regression adjusted for BMI, age, sex, ASA and ISS.

resultsA total of 1514 patients were included. Adjusted multivariate regression revealed BMI as being independently associated with an increased risk of ARDS (aOR 1.09 per kg/m

conclusionsA higher BMI was independently associated with ARDS, sepsis and MOF, but no independent association with mortality was detected in this cohort of adult trauma patients. This suggests that BMI may function as a clinically relevant risk marker.

Indexed as

Body Mass IndexMultiple Organ FailureObesityRespiratory Distress SyndromeSepsisWounds and InjuriesAdultFemaleGermanyHumansInjury Severity ScoreMaleMiddle AgedRetrospective StudiesRisk FactorsTrauma CentersARDSBMIMortalityMultiorgan failureObesityPneumoniaSepsisSexTrauma

Identifiers

PMID41896972
PMCPMC13063989

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.