ArticleBMC medicine2026
Impact of the family cohesion-centered frailty intervention on older gastric cancer patients: a non-randomized controlled trial.
Article in BMC medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Family Environment Factors Associated with Symptom Distress Among Korean Adolescents and Young Adults with Cancer: A Cross-Sectional Study.Current oncology (Toronto, Ont.) · 2026Article
- Health beliefs and quality of life in patients with gastric cancer: the chain mediating role of nutritional behaviors and nutritional status.Frontiers in oncology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundFrailty is highly prevalent among older gastric cancer patients and strongly associated with adverse postoperative outcomes. While frailty interventions have been implemented, few have focused on family cohesion as a pivotal aspect. This study aims to evaluate the effectiveness of a family cohesion-centered frailty intervention grounded in the Satir Family Therapy Model among for high-risk frailty older patients with gastric cancer.
methodsA non-randomized, time-based controlled trial was conducted in a tertiary hospital in China, with 79 participants and their family caregivers allocated according to sequential admission periods into an experimental group (n = 40) or a control group (n = 39). The intervention focused on enhancing family communication and cohesion. Frailty, family cohesion, self-efficacy, anxiety, depression, and quality of life were assessed on the day of admission (T0), at the end of the intervention, specifically at 4 weeks after surgery (T1), and 1 month after the completion of the intervention (T2). Analyses used generalized estimating equations with multiple imputation under an intention-to-treat framework, adjusting for demographic and clinical covariates. Moderation analyses tested three-way interactions.
resultsSignificant group by time interactions were observed for frailty, family cohesion, self-efficacy, anxiety, depression, and quality of life (all P < 0.05). Compared with usual care, the experimental group showed greater reductions in frailty, anxiety, and depression and was associated with improvement in family cohesion, self-efficacy, and quality of life, with effects strengthening at T2. Sensitivity analyses yielded consistent results. Limited moderating effects were identified for age, education, and TNM stage.
conclusionsThe family-cohesion-centered intervention was associated with multidimensional and sustained improvements among older gastric cancer patients at high risk of frailty. By integrating the Satir Family Therapy Model into perioperative care, this program may represent a feasible family-based approach that could contribute to optimizing frailty management and postoperative recovery. However, the non-randomized, time-based controlled design may introduce potential biases, including from secular trends or contamination; such biases could affect the estimates in either direction. Further randomized controlled trials are needed to verify this. TRIAL REGISTRATIONS: ChiCTR2400082744.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.