ArticleBMC neurology2026
Olfactory dysfunction in essential tremor with rest tremor: a cross-sectional comparison with parkinson's disease and essential tremor.
Article in BMC neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOlfactory dysfunction is a recognized non-motor feature of Parkinson’s disease (PD) and has also been described in essential tremor (ET). However, olfaction in essential tremor with rest tremor (ET + RT), a recently defined subtype, remains insufficiently explored.
objectivesTo assess olfactory function in patients with ET + RT and to compare their olfactory performance with those of patients with PD, ET, and healthy controls.
methodsThis cross-sectional study included 125 participants: 71 with tremor-dominant PD, 16 with ET, 16 with ET + RT, and 22 age- and sex-matched healthy controls. PD severity was assessed using the Hoehn and Yahr scale and the Unified Parkinson’s Disease Rating Scale (UPDRS). Tremor severity in ET was evaluated with the Fahn–Tolosa–Marin Tremor Rating Scale, while ET + RT patients were assessed using UPDRS Part III due to rest tremor. Olfactory function was evaluated using the Connecticut Chemosensory Clinical Research Center test.
resultsMedian olfactory scores were lowest in the PD group, followed by ET + RT, ET, and controls. PD patients had significantly lower scores than ET patients and healthy controls. ET + RT patients had significantly lower scores than controls. No statistically significant differences were observed between PD and ET + RT or between ET and ET + RT.
conclusionET + RT patients demonstrated numerically lower olfactory scores than patients with isolated ET, although the difference was not statistically significant. Olfactory scores in ET + RT were intermediate between ET and PD. Given the cross-sectional design, limited sample size, and absence of dopaminergic imaging, these findings should be interpreted cautiously and do not allow conclusions regarding longitudinal disease progression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.