Evidence map›Paper›PMID 41896642›Full record

ArticleScientific reports2026

Epidemiology and cardiometabolic care in adults with ASCVD and high 10-year ASCVD risk: 2021 WHO STEPS study in Iran.

Hossein Farrokhpour, Maryam Nasserinejad, Naser Ahmadi, Ali Golestani, Mohammad Keykhaei, Sina Azadnajafabad, Arya Aminorroaya, Mohammadreza Naderian, Nazila Rezaei, Shirin Djalalinia and 10 more

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Hossein Farrokhpour *Non-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Maryam Nasserinejad *Non-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Naser AhmadiNon-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Ali GolestaniNon-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad KeykhaeiNon-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Sina AzadnajafabadNon-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Arya AminorroayaNon-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mohammadreza NaderianNon-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Nazila RezaeiNon-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Shirin DjalaliniaDevelopment of Research and Technology Center, Deputy of Research and Technology, Ministry of Health and Medical Education, Tehran, Iran.
Yosef FarziNon-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad-Mahdi RashidiNon-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Negar RezaeiNon-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Erfan GhasemiNon-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Elham AbdolhamidiNon-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Moein YoosefiNon-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Ameneh KazemiEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Rosa HaghshenasNon-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mohamad Taghi MajnoonDivision of Pediatric Cardiology, Pediatrics Center of Excellence, School of Medicine, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Farshad FarzadfarNon-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. f-farzadfar@tums.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of mortality and health burden worldwide. We aimed to assess ASCVD epidemiology, 10-year risk, and cardiometabolic care using nationally representative data in Iran. Using the 2021 Iran STEPS study, a cross-sectional analysis was conducted to evaluate ASCVD (self-reported myocardial infarction, angina, revascularization, or stroke) prevalence and annual event rate. The 2013 AHA/ACC pooled cohort equations estimated 10-year ASCVD risk in 10,298 participants aged 40-75 without ASCVD. Cardiometabolic care for hypertension, diabetes mellitus (DM), and hypercholesterolemia was assessed, along with statin use and cardiovascular health (CVH) metrics. Among 27,822 participants, representing 57.5 million adults, ASCVD prevalence was 7.4%. Among those without ASCVD, 19.1% had an intermediate and 5.4% had a high ASCVD risk. In the ASCVD group, hypertension and DM affected 77.0% and 34.7%, yet only 12.5% and 14.3% of the entire ASCVD group had them controlled, respectively. In adults without ASCVD, 2.9-5.3% of the entire risk groups achieved hypertension targets, 2.5-16.8% achieved glycemic targets, and 7.7-16.7% achieved lipid goals, despite condition prevalence spanning 47.4-94.4% for hypertension, 7.2-59.3% for DM, and 33.5-48.7% for hypercholesterolemia. CVH metrics were also unfavorable. The study revealed a high ASCVD burden and future risks with gaps in coverage, treatment, and control.

Indexed as

AtherosclerosisCardiovascular DiseasesAdultAgedCross-Sectional StudiesDiabetes MellitusFemaleHumansHypercholesterolemiaHypertensionIranMaleMiddle AgedPrevalenceRisk FactorsASCVDAtherosclerotic cardiovascular diseasesCardiometabolic risk factorsEpidemiologyIran

Identifiers

PMID41896642
PMCPMC13039966

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