Evidence map›Paper›PMID 41896514›Full record

SynthesisAlimentary pharmacology & therapeutics2026

Meta-Analysis: Prevalence and Incidence of Gastroparesis Following Lung or Heart Transplantation.

Mohamed H Eldesouki, Mohamed Mahmoud Marey, Mohamed Ahmed Ali, Amany Mahmoud Genidy, Mohamed Hesham Gamal, Ali M Othman, Ahmed N Mohamed, Ahmed Al Qady, Manuel A Amaris, Amol Sharma

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Alimentary pharmacology & therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mohamed H EldesoukiDepartment of Internal Medicine, New York Medical College, St Michael Medical Center, Newark, New Jersey, USA.ORCID https://orcid.org/0009-0009-6662-5883
Mohamed Mahmoud MareyDepartment of Internal Medicine, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Mohamed Ahmed AliQena Faculty of Medicine, Qena University, Qena, Egypt.
Amany Mahmoud GenidyFaculty of medicine, Tanta University, Tanta, Egypt.ORCID https://orcid.org/0009-0003-6977-9569
Mohamed Hesham GamalFaculty of medicine, Tanta University, Tanta, Egypt.
Ali M OthmanDepartment of Internal Medicine, Faculty of Medicine, Kafr El-Sheik University, Kafr El-Sheik, Egypt.
Ahmed N MohamedDivision of Gastroenterology and Hepatology, Cleveland Clinic Foundation, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0001-9605-1539
Ahmed Al QadyDivision of Gastroenterology and Hepatology, Department of Internal Medicine, University of Florida, Gainesville, Florida, USA.
Manuel A AmarisDivision of Gastroenterology and Hepatology, Department of Internal Medicine, University of Florida, Gainesville, Florida, USA.
Amol SharmaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of South Carolina, Charleston, South Carolina, USA.ORCID https://orcid.org/0000-0002-5843-1220

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastroparesis is a recognized complication after thoracic organ transplantation that impairs nutrition, medication absorption, and graft outcomes.

aimThis study aimed to quantify the risk of gastroparesis following lung (LT) and combined heart-lung transplantation (HLT).

methodsA systematic search of PubMed, Embase, Scopus, and Web of Science from inception to January 2025 identified studies reporting gastroparesis after LT or HLT in adult cohorts with objective diagnostic testing. Random-effects meta-analysis was used to pool prevalence and incidence, with subgroup analyses by transplant type, and diagnostic modality, and meta-regression asessing the effects of age and sex.

resultsTwenty-one studies, including 2888 patients, met the inclusion criteria. The pooled prevalence of gastroparesis was 31.87% (95% CI: 19.88-46.87). Subgroup analysis revealed a higher prevalence of gastroparesis in combined HLT recipients (44.89%, 95% CI: 17.05-76.35) compared to LT only (26.95%, 95% CI: 15.46-42.68), though this difference was not statistically significant (p = 0.31). The overall incidence was 25.67% (95% CI: 15.07-40.41), with HLT recipients showing a higher incidence (35.79%, 95% CI: 20.73-54.29) than LT only (19.38%, 95% CI: 8.3-38.9).

conclusionGastroparesis affects nearly one-third of thoracic transplant recipients, with a numerically higher burden after HLT transplantation. There was no association between age and gender and the prevalence of post-transplant gastroparesis.

Indexed as

GastroparesisHeart-Lung TransplantationHeart TransplantationLung TransplantationPostoperative ComplicationsAdultFemaleHumansIncidenceMalePrevalenceRisk Factorsgastroparesisheart–lung transplantationlung transplantation

Identifiers

PMID41896514
PMCPMC13127852

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.