Evidence map›Paper›PMID 41896473›Full record

ArticleInternal and emergency medicine2026

Clinical significance of head CT scan in patients admitted to the emergency department with mild head trauma.

Marco Baldrighi, Luca Molinari, Demetrio Luzzi, Alice Rubinetti, Danila Azzolina, Luca Rousseau, Domenico Urzia, Alessandra Galbiati, Michela Beltrame, Martina Alfano and 9 more

Abstract read
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In one paragraph

Article in Internal and emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Marco BaldrighiDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy. marco.baldrighi@maggioreosp.novara.it.ORCID http://orcid.org/0000-0002-5595-6224
Luca MolinariDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy.
Demetrio LuzziDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy.
Alice RubinettiDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy.
Danila AzzolinaDepartment of Environmental and Preventive Science, University of Ferrara, Ferrara, Italy.
Luca RousseauDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy.
Domenico UrziaDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy.
Alessandra GalbiatiDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy.
Michela BeltrameDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy.
Martina AlfanoDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy.
Francesca Maria GiolittiDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy.
Claudia CiceroneDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy.
Giacomo IannantuoniDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy.
Luigi Mario CastelloDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy.
Filippo PatruccoDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy.
Pier Paolo SainaghiDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy.
Gian Carlo AvanziDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy.
Mattia BellanDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy.
Francesco GavelliDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Head computed tomography (CT) scan is the gold standard for early diagnosis of brain injuries in the Emergency Department (ED), but clinically important injuries after a mild head trauma (MHT) are rare. This study aims to evaluate the impact of head CTs on the management of patients presenting to the ED with MHT. In this prospective observational study, we enrolled adult patients admitted to the ED of a medium-size University Hospital for MHT. Patients were evaluated at the time of admission and then at 6-24-48-72 h (if still in the ED). A 90-day telephone follow-up was performed. The primary composite endpoint was a change in patients' management (hospitalization, modifications in pharmacotherapy or invasive treatments) following a CT. Between June 2021 and July 2023 we enrolled 508 patients. At least 1 CT was performed in 454 patients (89.4%), and the first CT revealed a brain injury in 87 (19.2%) of them. At least another CT was repeated in the first 24 h in 144 patients; delayed injuries were observed in 4 cases only, with no clinical impact. The cumulative number of CTs performed throughout the study was 620, but only 24 of them (3.9%) had a clinical impact, and none of the patients underwent neurosurgery. The incidence of intracranial injuries requiring admission or treatments was 4.5%. In conclusion, the incidence of brain injuries requiring treatment was very low, and most of the CTs had no clinical impact.

Indexed as

Brain computed tomographyEmergency departmentMild head injuryMild head traumaMild traumatic brain injury

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.