ArticleNeuroradiology2026
Impact of CT slice thickness on hematoma volume estimation by planimetry and ABC/2 in acute intracerebral hemorrhage.
Article in Neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeThe effect of CT slice thickness on hematoma volume estimation using planimetry and ABC/2 in intracerebral hemorrhage (ICH) has not been characterized. This study aimed to identify the optimal slice thickness and estimation methodology.
methodsConsecutive patients with ICH were retrospectively reviewed. Baseline and follow-up CT scans with slice thickness ≤ 1.25 mm were collected and resliced to thicknesses of 1.25 mm, 2.5 mm, and 5.0 mm. Hematoma volume was measured using planimetry and ABC/2, yielding six estimates per scan. Volume estimates by planimetry at 1.25 mm were used as the reference standard, and percentage errors were compared among the six estimates.
resultsA total of 255 patients were enrolled. Pairwise comparisons revealed that greater slice thickness was significantly associated with higher absolute percentage error in planimetry on both baseline and follow-up CT scans, except for 2.5 mm vs. 5.0 mm on follow-up. With ABC/2, only the pairs of 1.25 mm vs. 2.5 mm and 1.25 mm vs. 5.0 mm on baseline showed significant differences. Each planimetry–ABC/2 comparison demonstrated significant differences. Signed percentage errors with planimetry remained consistently within narrow ranges regardless of slice thickness, hematoma volume, and shape, whereas those with ABC/2 varied markedly depending on these factors.
conclusionThis study showed that CT slice thickness affects hematoma volume estimation, with differing impacts by methodology. In planimetry, percentage errors increased slightly with greater thickness but remained small. In ABC/2, percentage errors were generally larger, varied substantially with slice thickness, hematoma volume, and shape.
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