Evidence map›Paper›PMID 41896257›Full record

ArticleScientific reports2026

A novel superpixel based Vision Transformer for improving interpretability in glaucoma screening.

Jorge Hernández, Silvia Alayón, José F Sigut, Tinguaro Díaz-Alemán

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jorge HernándezDepartment of Computer Science and Systems Engineering, University of La Laguna, 38200, San Cristóbal de La Laguna, Santa Cruz de Tenerife, Spain. jhernanv@ull.edu.es.
Silvia AlayónDepartment of Computer Science and Systems Engineering, University of La Laguna, 38200, San Cristóbal de La Laguna, Santa Cruz de Tenerife, Spain.
José F SigutDepartment of Computer Science and Systems Engineering, University of La Laguna, 38200, San Cristóbal de La Laguna, Santa Cruz de Tenerife, Spain.
Tinguaro Díaz-AlemánDepartment of Ophthalmology, Canary Islands University Hospital, 38320, Santa Cruz de Tenerife, Santa Cruz de Tenerife, Spain.

Funding

Canary Islands Agency for Research, Innovation and Information Society of the Regional Ministry of Economy, Knowledge and Employment, and by the European Social Fund (ESF) Integrated Operational Programme of the Canary Islands 2014-2020 TESIS2022010056Canary Islands Agency for Research, Innovation and the Information Society (ACIISI) and by the European Regional Development Fund within the framework of the FEDER programme Canarias 2021-2027 PROID2024010027
6 · The paper itself

Abstract

Interpretability remains one of the major challenges in the clinical adoption of deep learning models for medical image analysis. In ophthalmology, particularly for glaucoma screening, explainable artificial intelligence (XAI) methods are essential for ensuring trust and diagnostic transparency. This study introduces the Superpixel-based Vision Transformer (SpxViT), a model designed to enhance interpretability while maintaining competitive accuracy. SpxViT replaces the traditional fixed grid tokenization of Vision Transformers. (ViTs) with a superpixel-based approach that preserves semantic boundaries within the retinal image. Two variants, SpxViT_fix and SpxViT_var, were evaluated on public and private glaucoma datasets. Results demonstrate that SpxViT achieves comparable accuracy to ViT-B/16 (91.9% vs. 92.5%) while producing more clinically consistent attention maps focused on the optic disc and cup.

Indexed as

GlaucomaImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedArtificial IntelligenceDeep LearningHumansOptic DiskAttention mapsExplainable AI (XAI)Glaucoma screeningInterpretabilityOphthalmologySuperpixelsVision Transformer (ViT)

Identifiers

PMID41896257
PMCPMC13039723

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.