Evidence map›Paper›PMID 41896211›Full record

ArticleNature communications2026

Thermosensory reconfiguration of the auxin transcriptional pathway to drive root cell growth.

María Belén Borniego, Matías Ezequiel Pereyra, Katelyn Sageman-Furnas, Andrés Hugo Rossi, Edward G Wilkinson, Lucia C Strader, Jorge J Casal

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

María Belén Borniego *Facultad de Agronomía, Instituto de Investigaciones Fisiológicas y Ecológicas Vinculadas a la Agricultura (IFEVA), Universidad de Buenos Aires, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.ORCID http://orcid.org/0000-0001-5160-5788
Matías Ezequiel Pereyra *Facultad de Agronomía, Instituto de Investigaciones Fisiológicas y Ecológicas Vinculadas a la Agricultura (IFEVA), Universidad de Buenos Aires, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.ORCID http://orcid.org/0000-0002-5924-5497
Katelyn Sageman-FurnasBiology Department, Duke University, Durham, NC, USA.ORCID http://orcid.org/0000-0003-2878-2027
Andrés Hugo RossiFundación Instituto Leloir, Instituto de Investigaciones Bioquímicas de Buenos Aires, CONICET, Buenos Aires, Argentina.
Edward G WilkinsonBiology Department, Duke University, Durham, NC, USA.
Lucia C StraderBiology Department, Duke University, Durham, NC, USA.ORCID http://orcid.org/0000-0002-7600-7204
Jorge J CasalFacultad de Agronomía, Instituto de Investigaciones Fisiológicas y Ecológicas Vinculadas a la Agricultura (IFEVA), Universidad de Buenos Aires, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina. casal@ifeva.edu.ar.ORCID http://orcid.org/0000-0001-6525-8414

Funding

Ministry of Science, Technology and Productive Innovation, Argentina | Agencia Nacional de Promoción Científica y Tecnológica (National Agency for Science and Technology, Argentina) PICT-2021-I-A-01070University of Buenos Aires | Secretaría de Ciencia y Técnica, Universidad de Buenos Aires (Secretaría de Ciencia y Técnica de la Universidad de Buenos Aires) 20020220300111BA
6 · The paper itself

Abstract

Elevated temperatures enhance plant root growth. We find that cell elongation significantly contributes to this response. While mutations in the auxin transcriptional pathway impair warmth-induced cell elongation, exogenous auxin inhibits this growth. Intriguingly, warmth increases auxin levels and the nuclear accumulation of TIR1/AFB2/AFB3, alongside Aux/IAA stabilisation. This apparent paradox is explained by the concurrent increase in nuclear AFB1, which stabilises Aux/IAAs and promotes cell elongation. Notably, despite enhancing Aux/IAA stability, warmth also promotes ARF transcriptional activity. ARF7/19 are essential for warmth-induced cell growth and its inhibition by exogenous auxin. Warmth directly modulates ARF7/19 by reducing oligomerisation and cytoplasmic condensation, thereby enhancing their nuclear accumulation. This mechanism effectively repurposes the auxin pathway to regulate root cell growth in response to temperature.

Indexed as

ArabidopsisIndoleacetic AcidsPlant RootsArabidopsis ProteinsCell NucleusF-Box ProteinsGene Expression Regulation, PlantMutationProtein Serine-Threonine KinasesReceptors, Cell SurfaceSignal TransductionTemperatureTranscription FactorsTranscription, GeneticArabidopsis ProteinsARF7 protein, ArabidopsisAT1G66150 protein, ArabidopsisF-Box ProteinsIndoleacetic AcidsProtein Serine-Threonine KinasesReceptors, Cell SurfaceTIR1 protein, ArabidopsisTranscription Factors

Identifiers

PMID41896211
PMCPMC13031317

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.