Evidence map›Paper›PMID 41896179›Full record

ArticlePlant biotechnology journal2026

Genomic and Transcriptomic Analyses Provide Insights Into Erysiphe necator Pathogenicity and Grapevine Response.

Bo Mu, Ruixin Tang, Zhaolin Teng, Jinfu Chen, Kaicheng Cui, Feng Wei, Wenxiang Kong, Shunyuan Xiao, Xiangnan Xu, Jia-Yue Feng and 1 more

Abstract read
In one paragraph

Article in Plant biotechnology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bo MuHainan Institute of Northwest A&F University, Sanya, Hainan, China.
Ruixin TangHainan Institute of Northwest A&F University, Sanya, Hainan, China.
Zhaolin TengHainan Institute of Northwest A&F University, Sanya, Hainan, China.
Jinfu ChenHainan Institute of Northwest A&F University, Sanya, Hainan, China.
Kaicheng CuiHainan Institute of Northwest A&F University, Sanya, Hainan, China.
Feng WeiHainan Institute of Northwest A&F University, Sanya, Hainan, China.
Wenxiang KongHainan Institute of Northwest A&F University, Sanya, Hainan, China.
Shunyuan XiaoInstitute for Bioscience and Biotechnology Research, University of Maryland, Rockville, Maryland, USA.
Xiangnan XuInstitute of Plant Nutrition, Resources and Environment, Beijing Academy of Agriculture and Forestry Sciences, China.
Jia-Yue FengHainan Institute of Northwest A&F University, Sanya, Hainan, China.
Ying-Qiang WenHainan Institute of Northwest A&F University, Sanya, Hainan, China.

Funding

Key Research and Development Projects of Shaanxi Province 2023-YBNY-059National Key Research and Development Program of China 2019YFD1000102-12National Natural Science Foundation of China 31972986National Natural Science Foundation of China 32272670
6 · The paper itself

Abstract

Grapevine powdery mildew, caused by the fungus Erysiphe necator, is one of the most prevalent obligate biotrophic pathogens in vineyards, posing a significant threat to grape production. Despite its impact, research on E. necator pathogenicity and grapevine responses remains limited. In this study, we assembled a high-quality 69.93 Mb genome for E. necator isolate NAFU1, identifying 248 candidate-secreted effector proteins (CSEPs). RNA-Seq analysis of E. necator NAFU1 and the grapevine host during various infection stages revealed that expression of many genes, especially those encoding CSEPs, was induced in planta to facilitate host colonisation. Detailed analysis identified CSEP118 as a key highly induced effector gene, plays an important role in suppression of host defence. CSEP118 appears to interfere with the grapevine defence response to infection by targeting VviTrxz, a grapevine thioredoxin. Comparative transcriptome analysis of susceptible (Vitis vinifera cv. Cabernet Sauvignon) and resistant (Vitis piasezkii accession Baishui-40) grapevines upon infection by E. necator identified VviTCP14, encoding a transcription factor, to be a likely negative regulator of grapevine resistance against E. necator. Supporting this, VviTCP14-silenced plants exhibited increased expression of resistance-related genes such as those encoding stilbene synthases (STSs) and elevated stilbene contents when compared with the wild type grapevine. In summary, this study utilised a multi-omics approach to understand mechanisms underlying E. necator effector-triggered suppression of grapevine immunity and transcriptional regulation of host defence response during grapevine-powdery mildew interaction. The regulatory mechanisms uncovered in this study should provide valuable insights for improving grapevine resistance to powdery mildew.

Indexed as

ErysiphePlant DiseasesVitisFungal ProteinsGene Expression ProfilingGenomicsHost-Pathogen InteractionsPlant ProteinsTranscriptomeFungal ProteinsPlant ProteinsCSEP118genomegrapevinepowdery mildewRNA‐seqVviTCP14

Identifiers

PMID41896179
PMCPMC13278547

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.